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Extracellular Heparan 6-O-Endosulfatases SULF1 and SULF2 in Head and Neck Squamous Cell Carcinoma and Other Malignancies

SIMPLE SUMMARY: 6-O-endosulfatases, SULF1 and SULF2, are oncogenic in multiple malignancies and are associated with poor survival outcomes. SULF1 is one of the most consistently unregulated enzymes in HNSCC tissues even though its expression in the cancer cells is marginal. Our PDX and RNA scope exp...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Ahn, Jaeil, Edwards, Nathan J., Benicky, Julius, Rozeboom, Aaron M., Davidson, Bruce, Karamboulas, Christina, Nixon, Kevin C. J., Ailles, Laurie, Goldman, Radoslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688903/
https://www.ncbi.nlm.nih.gov/pubmed/36428645
http://dx.doi.org/10.3390/cancers14225553