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The Absence of Permanent Sensorineural Hearing Loss in a Cohort of Children with SARS-CoV-2 Infection and the Importance of Performing the Audiological “Work-Up”

Background: Currently, the novel coronavirus (SARS-CoV-2) causes an acute respiratory illness named COVID-19 and is a controversial risk factor for hearing loss (HL). Herein, we aim to describe the associated symptoms and to evaluate hearing function in the COVID-19 pediatric population. Methods: A...

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Autores principales: Malesci, Rita, Rizzo, Davide, Del Vecchio, Valeria, Serra, Nicola, Tarallo, Giuseppe, D’Errico, Domenico, Coronella, Valentina, Bussu, Francesco, Lo Vecchio, Andrea, Auletta, Gennaro, Franzè, Annamaria, Fetoni, Anna Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689077/
https://www.ncbi.nlm.nih.gov/pubmed/36360409
http://dx.doi.org/10.3390/children9111681
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author Malesci, Rita
Rizzo, Davide
Del Vecchio, Valeria
Serra, Nicola
Tarallo, Giuseppe
D’Errico, Domenico
Coronella, Valentina
Bussu, Francesco
Lo Vecchio, Andrea
Auletta, Gennaro
Franzè, Annamaria
Fetoni, Anna Rita
author_facet Malesci, Rita
Rizzo, Davide
Del Vecchio, Valeria
Serra, Nicola
Tarallo, Giuseppe
D’Errico, Domenico
Coronella, Valentina
Bussu, Francesco
Lo Vecchio, Andrea
Auletta, Gennaro
Franzè, Annamaria
Fetoni, Anna Rita
author_sort Malesci, Rita
collection PubMed
description Background: Currently, the novel coronavirus (SARS-CoV-2) causes an acute respiratory illness named COVID-19 and is a controversial risk factor for hearing loss (HL). Herein, we aim to describe the associated symptoms and to evaluate hearing function in the COVID-19 pediatric population. Methods: A retrospective cross-sectional observational study was carried out on 37 children who contracted COVID-19 infection with no previous audio-vestibular disorders. Clinical data on the infections were collected, and an audiological assessment of all affected children was performed by using different diagnostic protocols according to their age. Results: Fever, upper respiratory and gastrointestinal manifestations were common presentations of infection. Audiological function was normal in 30 (81.08%) children, while 7 children showed an increased hearing threshold: 6 (16.21%) had transient conductive hearing loss (CHL) due to middle ear effusion and normalized at the follow-up and 1 had sensorineural hearing loss (SNHL). A single child was affected by bilateral SNHL (2.7%); however, he underwent a complete audiological work-up leading to a diagnosis of genetic HL due to a MYO6 gene mutation which is causative of progressive or late onset SNHL. Conclusions: HL needs to be considered among the manifestations of COVID-19 in children, nevertheless, we found cases of transient CHL. The onset of HL during or following COVID-19 infection does not eliminate the indication for maintaining audiological surveillance and audiological work-ups, including genetic diagnosis, to avoid the risk of mistaking other causes of HL.
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spelling pubmed-96890772022-11-25 The Absence of Permanent Sensorineural Hearing Loss in a Cohort of Children with SARS-CoV-2 Infection and the Importance of Performing the Audiological “Work-Up” Malesci, Rita Rizzo, Davide Del Vecchio, Valeria Serra, Nicola Tarallo, Giuseppe D’Errico, Domenico Coronella, Valentina Bussu, Francesco Lo Vecchio, Andrea Auletta, Gennaro Franzè, Annamaria Fetoni, Anna Rita Children (Basel) Article Background: Currently, the novel coronavirus (SARS-CoV-2) causes an acute respiratory illness named COVID-19 and is a controversial risk factor for hearing loss (HL). Herein, we aim to describe the associated symptoms and to evaluate hearing function in the COVID-19 pediatric population. Methods: A retrospective cross-sectional observational study was carried out on 37 children who contracted COVID-19 infection with no previous audio-vestibular disorders. Clinical data on the infections were collected, and an audiological assessment of all affected children was performed by using different diagnostic protocols according to their age. Results: Fever, upper respiratory and gastrointestinal manifestations were common presentations of infection. Audiological function was normal in 30 (81.08%) children, while 7 children showed an increased hearing threshold: 6 (16.21%) had transient conductive hearing loss (CHL) due to middle ear effusion and normalized at the follow-up and 1 had sensorineural hearing loss (SNHL). A single child was affected by bilateral SNHL (2.7%); however, he underwent a complete audiological work-up leading to a diagnosis of genetic HL due to a MYO6 gene mutation which is causative of progressive or late onset SNHL. Conclusions: HL needs to be considered among the manifestations of COVID-19 in children, nevertheless, we found cases of transient CHL. The onset of HL during or following COVID-19 infection does not eliminate the indication for maintaining audiological surveillance and audiological work-ups, including genetic diagnosis, to avoid the risk of mistaking other causes of HL. MDPI 2022-11-01 /pmc/articles/PMC9689077/ /pubmed/36360409 http://dx.doi.org/10.3390/children9111681 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Malesci, Rita
Rizzo, Davide
Del Vecchio, Valeria
Serra, Nicola
Tarallo, Giuseppe
D’Errico, Domenico
Coronella, Valentina
Bussu, Francesco
Lo Vecchio, Andrea
Auletta, Gennaro
Franzè, Annamaria
Fetoni, Anna Rita
The Absence of Permanent Sensorineural Hearing Loss in a Cohort of Children with SARS-CoV-2 Infection and the Importance of Performing the Audiological “Work-Up”
title The Absence of Permanent Sensorineural Hearing Loss in a Cohort of Children with SARS-CoV-2 Infection and the Importance of Performing the Audiological “Work-Up”
title_full The Absence of Permanent Sensorineural Hearing Loss in a Cohort of Children with SARS-CoV-2 Infection and the Importance of Performing the Audiological “Work-Up”
title_fullStr The Absence of Permanent Sensorineural Hearing Loss in a Cohort of Children with SARS-CoV-2 Infection and the Importance of Performing the Audiological “Work-Up”
title_full_unstemmed The Absence of Permanent Sensorineural Hearing Loss in a Cohort of Children with SARS-CoV-2 Infection and the Importance of Performing the Audiological “Work-Up”
title_short The Absence of Permanent Sensorineural Hearing Loss in a Cohort of Children with SARS-CoV-2 Infection and the Importance of Performing the Audiological “Work-Up”
title_sort absence of permanent sensorineural hearing loss in a cohort of children with sars-cov-2 infection and the importance of performing the audiological “work-up”
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689077/
https://www.ncbi.nlm.nih.gov/pubmed/36360409
http://dx.doi.org/10.3390/children9111681
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