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CT-Guided Radiofrequency Thermal Ablation for the Treatment of Atypical, Early-Onset Osteoid Osteoma in Children Younger than 4 Years Old: Single-Institution Experience and Literature Review

The aim of our study is to report our experience on CT-guided radiofrequency ablation (RFA) for osteoid osteoma (OO) in children under 4 years of age and to review the literature regarding this atypical, early onset of the disease. We retrospectively reviewed the clinical and radiological records of...

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Autores principales: Papalexis, Nicolas, Peta, Giuliano, Ponti, Federico, Tuzzato, Gianmarco, Colangeli, Marco, Facchini, Giancarlo, Spinnato, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689092/
https://www.ncbi.nlm.nih.gov/pubmed/36428872
http://dx.doi.org/10.3390/diagnostics12112812
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author Papalexis, Nicolas
Peta, Giuliano
Ponti, Federico
Tuzzato, Gianmarco
Colangeli, Marco
Facchini, Giancarlo
Spinnato, Paolo
author_facet Papalexis, Nicolas
Peta, Giuliano
Ponti, Federico
Tuzzato, Gianmarco
Colangeli, Marco
Facchini, Giancarlo
Spinnato, Paolo
author_sort Papalexis, Nicolas
collection PubMed
description The aim of our study is to report our experience on CT-guided radiofrequency ablation (RFA) for osteoid osteoma (OO) in children under 4 years of age and to review the literature regarding this atypical, early onset of the disease. We retrospectively reviewed the clinical and radiological records of the patients treated with CT-guided RFA for OO at our institution (2006–2021), including those under 4 years of age. Data regarding technical success, clinical success, and biopsy diagnostic yield were collected. Moreover, we performed a literature review including previous articles on early-onset OO. We found only 12 patients that were under 4 years of age (12/842–1.4%) at the time of RFA treatment: 4 F and 8 M, mean age at the time of the treatment 35.3 months (range 22–46 months). The mean follow-up was 22.8 months (range 6–96 months). Technical success was achieved in all cases (12/12). In all patients (12/12), a complete remission of the pain symptoms was achieved at clinical follow-up controls. No recurrence of pain or complications were documented. The histopathological diagnosis was confirmed in 4 patients (4/12–33.3%). Moreover, we found another 9 articles in the literature with a main focus on early-onset OO (<4 years old), with a total of 12 patients included; 6 of those patients (6/12–50%) were treated with CT-guided RFA, with success reported 5 cases (5/6–83.3%). Our series of cases treated at a single institution, together with the existing data from the literature, confirms that CT-guided RFA is effective and safe for the treatment of osteoid osteoma, even in atypical, early onset in children under 4 years of age.
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spelling pubmed-96890922022-11-25 CT-Guided Radiofrequency Thermal Ablation for the Treatment of Atypical, Early-Onset Osteoid Osteoma in Children Younger than 4 Years Old: Single-Institution Experience and Literature Review Papalexis, Nicolas Peta, Giuliano Ponti, Federico Tuzzato, Gianmarco Colangeli, Marco Facchini, Giancarlo Spinnato, Paolo Diagnostics (Basel) Article The aim of our study is to report our experience on CT-guided radiofrequency ablation (RFA) for osteoid osteoma (OO) in children under 4 years of age and to review the literature regarding this atypical, early onset of the disease. We retrospectively reviewed the clinical and radiological records of the patients treated with CT-guided RFA for OO at our institution (2006–2021), including those under 4 years of age. Data regarding technical success, clinical success, and biopsy diagnostic yield were collected. Moreover, we performed a literature review including previous articles on early-onset OO. We found only 12 patients that were under 4 years of age (12/842–1.4%) at the time of RFA treatment: 4 F and 8 M, mean age at the time of the treatment 35.3 months (range 22–46 months). The mean follow-up was 22.8 months (range 6–96 months). Technical success was achieved in all cases (12/12). In all patients (12/12), a complete remission of the pain symptoms was achieved at clinical follow-up controls. No recurrence of pain or complications were documented. The histopathological diagnosis was confirmed in 4 patients (4/12–33.3%). Moreover, we found another 9 articles in the literature with a main focus on early-onset OO (<4 years old), with a total of 12 patients included; 6 of those patients (6/12–50%) were treated with CT-guided RFA, with success reported 5 cases (5/6–83.3%). Our series of cases treated at a single institution, together with the existing data from the literature, confirms that CT-guided RFA is effective and safe for the treatment of osteoid osteoma, even in atypical, early onset in children under 4 years of age. MDPI 2022-11-16 /pmc/articles/PMC9689092/ /pubmed/36428872 http://dx.doi.org/10.3390/diagnostics12112812 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Papalexis, Nicolas
Peta, Giuliano
Ponti, Federico
Tuzzato, Gianmarco
Colangeli, Marco
Facchini, Giancarlo
Spinnato, Paolo
CT-Guided Radiofrequency Thermal Ablation for the Treatment of Atypical, Early-Onset Osteoid Osteoma in Children Younger than 4 Years Old: Single-Institution Experience and Literature Review
title CT-Guided Radiofrequency Thermal Ablation for the Treatment of Atypical, Early-Onset Osteoid Osteoma in Children Younger than 4 Years Old: Single-Institution Experience and Literature Review
title_full CT-Guided Radiofrequency Thermal Ablation for the Treatment of Atypical, Early-Onset Osteoid Osteoma in Children Younger than 4 Years Old: Single-Institution Experience and Literature Review
title_fullStr CT-Guided Radiofrequency Thermal Ablation for the Treatment of Atypical, Early-Onset Osteoid Osteoma in Children Younger than 4 Years Old: Single-Institution Experience and Literature Review
title_full_unstemmed CT-Guided Radiofrequency Thermal Ablation for the Treatment of Atypical, Early-Onset Osteoid Osteoma in Children Younger than 4 Years Old: Single-Institution Experience and Literature Review
title_short CT-Guided Radiofrequency Thermal Ablation for the Treatment of Atypical, Early-Onset Osteoid Osteoma in Children Younger than 4 Years Old: Single-Institution Experience and Literature Review
title_sort ct-guided radiofrequency thermal ablation for the treatment of atypical, early-onset osteoid osteoma in children younger than 4 years old: single-institution experience and literature review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689092/
https://www.ncbi.nlm.nih.gov/pubmed/36428872
http://dx.doi.org/10.3390/diagnostics12112812
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