Cargando…

Group Testing with Blocks of Positives and Inhibitors

The main goal of group testing is to identify a small number of specific items among a large population of items. In this paper, we consider specific items as positives and inhibitors and non-specific items as negatives. In particular, we consider a novel model called group testing with blocks of po...

Descripción completa

Detalles Bibliográficos
Autores principales: Bui, Thach V., Echizen, Isao, Kuribayashi, Minoru, Kojima, Tetsuya, Nguyen, Thuc D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689211/
https://www.ncbi.nlm.nih.gov/pubmed/36359652
http://dx.doi.org/10.3390/e24111562
_version_ 1784836473903644672
author Bui, Thach V.
Echizen, Isao
Kuribayashi, Minoru
Kojima, Tetsuya
Nguyen, Thuc D.
author_facet Bui, Thach V.
Echizen, Isao
Kuribayashi, Minoru
Kojima, Tetsuya
Nguyen, Thuc D.
author_sort Bui, Thach V.
collection PubMed
description The main goal of group testing is to identify a small number of specific items among a large population of items. In this paper, we consider specific items as positives and inhibitors and non-specific items as negatives. In particular, we consider a novel model called group testing with blocks of positives and inhibitors. A test on a subset of items is positive if the subset contains at least one positive and does not contain any inhibitors, and it is negative otherwise. In this model, the input items are linearly ordered, and the positives and inhibitors are subsets of small blocks (at unknown locations) of consecutive items over that order. We also consider two specific instantiations of this model. The first instantiation is that model that contains a single block of consecutive items consisting of exactly known numbers of positives and inhibitors. The second instantiation is the model that contains a single block of consecutive items containing known numbers of positives and inhibitors. Our contribution is to propose efficient encoding and decoding schemes such that the numbers of tests used to identify only positives or both positives and inhibitors are less than the ones in the state-of-the-art schemes. Moreover, the decoding times mostly scale to the numbers of tests that are significantly smaller than the state-of-the-art ones, which scale to both the number of tests and the number of items.
format Online
Article
Text
id pubmed-9689211
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96892112022-11-25 Group Testing with Blocks of Positives and Inhibitors Bui, Thach V. Echizen, Isao Kuribayashi, Minoru Kojima, Tetsuya Nguyen, Thuc D. Entropy (Basel) Article The main goal of group testing is to identify a small number of specific items among a large population of items. In this paper, we consider specific items as positives and inhibitors and non-specific items as negatives. In particular, we consider a novel model called group testing with blocks of positives and inhibitors. A test on a subset of items is positive if the subset contains at least one positive and does not contain any inhibitors, and it is negative otherwise. In this model, the input items are linearly ordered, and the positives and inhibitors are subsets of small blocks (at unknown locations) of consecutive items over that order. We also consider two specific instantiations of this model. The first instantiation is that model that contains a single block of consecutive items consisting of exactly known numbers of positives and inhibitors. The second instantiation is the model that contains a single block of consecutive items containing known numbers of positives and inhibitors. Our contribution is to propose efficient encoding and decoding schemes such that the numbers of tests used to identify only positives or both positives and inhibitors are less than the ones in the state-of-the-art schemes. Moreover, the decoding times mostly scale to the numbers of tests that are significantly smaller than the state-of-the-art ones, which scale to both the number of tests and the number of items. MDPI 2022-10-30 /pmc/articles/PMC9689211/ /pubmed/36359652 http://dx.doi.org/10.3390/e24111562 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bui, Thach V.
Echizen, Isao
Kuribayashi, Minoru
Kojima, Tetsuya
Nguyen, Thuc D.
Group Testing with Blocks of Positives and Inhibitors
title Group Testing with Blocks of Positives and Inhibitors
title_full Group Testing with Blocks of Positives and Inhibitors
title_fullStr Group Testing with Blocks of Positives and Inhibitors
title_full_unstemmed Group Testing with Blocks of Positives and Inhibitors
title_short Group Testing with Blocks of Positives and Inhibitors
title_sort group testing with blocks of positives and inhibitors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689211/
https://www.ncbi.nlm.nih.gov/pubmed/36359652
http://dx.doi.org/10.3390/e24111562
work_keys_str_mv AT buithachv grouptestingwithblocksofpositivesandinhibitors
AT echizenisao grouptestingwithblocksofpositivesandinhibitors
AT kuribayashiminoru grouptestingwithblocksofpositivesandinhibitors
AT kojimatetsuya grouptestingwithblocksofpositivesandinhibitors
AT nguyenthucd grouptestingwithblocksofpositivesandinhibitors