Multimodality Imaging Evaluation of Coronary IgG4-Related Disease: A “Tumor-Like” Cardiac Lesion

Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated fibro-inflammatory disorder. Coronary IgG4-RD has been scarcely reported and may present as “tumor-like” lesions. These pseudo-masses may be underdiagnosed mainly due to a vague clinical picture that can vary from complete lac...

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Detalles Bibliográficos
Autores principales: Lanzafame, Ludovica R. M., Carerj, Maria Ludovica, Rizzo, Giovanna, Minutoli, Fabio, Bucolo, Giuseppe M., Irrera, Natasha, Muscogiuri, Giuseppe, Sironi, Sandro, Blandino, Alfredo, D’Angelo, Tommaso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689228/
https://www.ncbi.nlm.nih.gov/pubmed/36428873
http://dx.doi.org/10.3390/diagnostics12112814
Descripción
Sumario:Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated fibro-inflammatory disorder. Coronary IgG4-RD has been scarcely reported and may present as “tumor-like” lesions. These pseudo-masses may be underdiagnosed mainly due to a vague clinical picture that can vary from complete lack of symptoms to acute coronary syndrome or sudden cardiac death. Early recognition of coronary IgG4-RD is essential to monitor disease activity and prevent life-threatening complications. We report a comprehensive non-invasive imaging evaluation of a patient affected by coronary IgG4-RD, which was diagnosed as an incidental finding during routine pre-laparoscopic cholecystectomy checkup. Non-invasive imaging revealed the presence of a peri-coronary soft-tissue mass that was stable at 12 months follow-up.

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