Cargando…
Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report
Background: We evaluated the efficacy of Cord Blood Platelet Gel (CBPG) in the regenerative reconstruction of the nasal septal tissue of a preterm infant undergoing non-invasive ventilation. Methods: A CBPC treatment was used to enhance the regeneration of the nasal septum of a premature patient in...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689260/ https://www.ncbi.nlm.nih.gov/pubmed/36421216 http://dx.doi.org/10.3390/children9111767 |
_version_ | 1784836486524305408 |
---|---|
author | Falsaperla, Raffaele Biondi, Giulia Marialidia Motta, Milena Gallerano, Pasquale Tancredi, Giusi Pavone, Piero Ruggieri, Martino |
author_facet | Falsaperla, Raffaele Biondi, Giulia Marialidia Motta, Milena Gallerano, Pasquale Tancredi, Giusi Pavone, Piero Ruggieri, Martino |
author_sort | Falsaperla, Raffaele |
collection | PubMed |
description | Background: We evaluated the efficacy of Cord Blood Platelet Gel (CBPG) in the regenerative reconstruction of the nasal septal tissue of a preterm infant undergoing non-invasive ventilation. Methods: A CBPC treatment was used to enhance the regeneration of the nasal septum of a premature patient in an experimental way, evaluating the efficacy described in the literature (selective bibliographic search in PubMed) of the use of blood products for non-transfusion purposes. Results: A partial but satisfactory regeneration of the patient’s nasal septum was observed. Using the free NIH Image J online software, we were able to calculate the regenerated surface (about 83% of the destroyed cartilage). Conclusions: The use of platelet gel has been a promising alternative to surgical treatment in patients with severe damage to the nasal septum. |
format | Online Article Text |
id | pubmed-9689260 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96892602022-11-25 Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report Falsaperla, Raffaele Biondi, Giulia Marialidia Motta, Milena Gallerano, Pasquale Tancredi, Giusi Pavone, Piero Ruggieri, Martino Children (Basel) Case Report Background: We evaluated the efficacy of Cord Blood Platelet Gel (CBPG) in the regenerative reconstruction of the nasal septal tissue of a preterm infant undergoing non-invasive ventilation. Methods: A CBPC treatment was used to enhance the regeneration of the nasal septum of a premature patient in an experimental way, evaluating the efficacy described in the literature (selective bibliographic search in PubMed) of the use of blood products for non-transfusion purposes. Results: A partial but satisfactory regeneration of the patient’s nasal septum was observed. Using the free NIH Image J online software, we were able to calculate the regenerated surface (about 83% of the destroyed cartilage). Conclusions: The use of platelet gel has been a promising alternative to surgical treatment in patients with severe damage to the nasal septum. MDPI 2022-11-17 /pmc/articles/PMC9689260/ /pubmed/36421216 http://dx.doi.org/10.3390/children9111767 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Falsaperla, Raffaele Biondi, Giulia Marialidia Motta, Milena Gallerano, Pasquale Tancredi, Giusi Pavone, Piero Ruggieri, Martino Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report |
title | Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report |
title_full | Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report |
title_fullStr | Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report |
title_full_unstemmed | Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report |
title_short | Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report |
title_sort | impressive nasal septum regeneration after cord blood platelet gel (cbpg) in extreme premature neonate with non-invasive ventilation: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689260/ https://www.ncbi.nlm.nih.gov/pubmed/36421216 http://dx.doi.org/10.3390/children9111767 |
work_keys_str_mv | AT falsaperlaraffaele impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport AT biondigiuliamarialidia impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport AT mottamilena impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport AT galleranopasquale impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport AT tancredigiusi impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport AT pavonepiero impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport AT ruggierimartino impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport |