Cargando…

Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report

Background: We evaluated the efficacy of Cord Blood Platelet Gel (CBPG) in the regenerative reconstruction of the nasal septal tissue of a preterm infant undergoing non-invasive ventilation. Methods: A CBPC treatment was used to enhance the regeneration of the nasal septum of a premature patient in...

Descripción completa

Detalles Bibliográficos
Autores principales: Falsaperla, Raffaele, Biondi, Giulia Marialidia, Motta, Milena, Gallerano, Pasquale, Tancredi, Giusi, Pavone, Piero, Ruggieri, Martino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689260/
https://www.ncbi.nlm.nih.gov/pubmed/36421216
http://dx.doi.org/10.3390/children9111767
_version_ 1784836486524305408
author Falsaperla, Raffaele
Biondi, Giulia Marialidia
Motta, Milena
Gallerano, Pasquale
Tancredi, Giusi
Pavone, Piero
Ruggieri, Martino
author_facet Falsaperla, Raffaele
Biondi, Giulia Marialidia
Motta, Milena
Gallerano, Pasquale
Tancredi, Giusi
Pavone, Piero
Ruggieri, Martino
author_sort Falsaperla, Raffaele
collection PubMed
description Background: We evaluated the efficacy of Cord Blood Platelet Gel (CBPG) in the regenerative reconstruction of the nasal septal tissue of a preterm infant undergoing non-invasive ventilation. Methods: A CBPC treatment was used to enhance the regeneration of the nasal septum of a premature patient in an experimental way, evaluating the efficacy described in the literature (selective bibliographic search in PubMed) of the use of blood products for non-transfusion purposes. Results: A partial but satisfactory regeneration of the patient’s nasal septum was observed. Using the free NIH Image J online software, we were able to calculate the regenerated surface (about 83% of the destroyed cartilage). Conclusions: The use of platelet gel has been a promising alternative to surgical treatment in patients with severe damage to the nasal septum.
format Online
Article
Text
id pubmed-9689260
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96892602022-11-25 Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report Falsaperla, Raffaele Biondi, Giulia Marialidia Motta, Milena Gallerano, Pasquale Tancredi, Giusi Pavone, Piero Ruggieri, Martino Children (Basel) Case Report Background: We evaluated the efficacy of Cord Blood Platelet Gel (CBPG) in the regenerative reconstruction of the nasal septal tissue of a preterm infant undergoing non-invasive ventilation. Methods: A CBPC treatment was used to enhance the regeneration of the nasal septum of a premature patient in an experimental way, evaluating the efficacy described in the literature (selective bibliographic search in PubMed) of the use of blood products for non-transfusion purposes. Results: A partial but satisfactory regeneration of the patient’s nasal septum was observed. Using the free NIH Image J online software, we were able to calculate the regenerated surface (about 83% of the destroyed cartilage). Conclusions: The use of platelet gel has been a promising alternative to surgical treatment in patients with severe damage to the nasal septum. MDPI 2022-11-17 /pmc/articles/PMC9689260/ /pubmed/36421216 http://dx.doi.org/10.3390/children9111767 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Falsaperla, Raffaele
Biondi, Giulia Marialidia
Motta, Milena
Gallerano, Pasquale
Tancredi, Giusi
Pavone, Piero
Ruggieri, Martino
Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report
title Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report
title_full Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report
title_fullStr Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report
title_full_unstemmed Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report
title_short Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report
title_sort impressive nasal septum regeneration after cord blood platelet gel (cbpg) in extreme premature neonate with non-invasive ventilation: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689260/
https://www.ncbi.nlm.nih.gov/pubmed/36421216
http://dx.doi.org/10.3390/children9111767
work_keys_str_mv AT falsaperlaraffaele impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport
AT biondigiuliamarialidia impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport
AT mottamilena impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport
AT galleranopasquale impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport
AT tancredigiusi impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport
AT pavonepiero impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport
AT ruggierimartino impressivenasalseptumregenerationaftercordbloodplateletgelcbpginextremeprematureneonatewithnoninvasiveventilationacasereport