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Piperazine Derivative Stabilizes Actin Filaments in Primary Fibroblasts and Binds G-Actin In Silico
Alzheimer’s disease (AD) is characterized by synaptic dysfunction, which is expressed through the loss of dendritic spines and changes in their morphology. Pharmacological compounds that are able to protect spines in the AD brain are suggested to be novel drugs that would be able to slow down the di...
Autores principales: | Zernov, Nikita, Ghamaryan, Viktor, Makichyan, Ani, Melenteva, Daria, Hunanyan, Lernik, Popugaeva, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689266/ https://www.ncbi.nlm.nih.gov/pubmed/36354665 http://dx.doi.org/10.3390/cimb44110353 |
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