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Piperazine Derivative Stabilizes Actin Filaments in Primary Fibroblasts and Binds G-Actin In Silico

Alzheimer’s disease (AD) is characterized by synaptic dysfunction, which is expressed through the loss of dendritic spines and changes in their morphology. Pharmacological compounds that are able to protect spines in the AD brain are suggested to be novel drugs that would be able to slow down the di...

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Detalles Bibliográficos
Autores principales: Zernov, Nikita, Ghamaryan, Viktor, Makichyan, Ani, Melenteva, Daria, Hunanyan, Lernik, Popugaeva, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689266/
https://www.ncbi.nlm.nih.gov/pubmed/36354665
http://dx.doi.org/10.3390/cimb44110353

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