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A Deep Learning Algorithm for Radiographic Measurements of the Hip in Adults—A Reliability and Agreement Study
Hip dysplasia (HD) is a frequent cause of hip pain in skeletally mature patients and may lead to osteoarthritis (OA). An accurate and early diagnosis may postpone, reduce or even prevent the onset of OA and ultimately hip arthroplasty at a young age. The overall aim of this study was to assess the r...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689405/ https://www.ncbi.nlm.nih.gov/pubmed/36359441 http://dx.doi.org/10.3390/diagnostics12112597 |
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author | Jensen, Janni Graumann, Ole Overgaard, Søren Gerke, Oke Lundemann, Michael Haubro, Martin Haagen Varnum, Claus Bak, Lene Rasmussen, Janne Olsen, Lone B. Rasmussen, Benjamin S. B. |
author_facet | Jensen, Janni Graumann, Ole Overgaard, Søren Gerke, Oke Lundemann, Michael Haubro, Martin Haagen Varnum, Claus Bak, Lene Rasmussen, Janne Olsen, Lone B. Rasmussen, Benjamin S. B. |
author_sort | Jensen, Janni |
collection | PubMed |
description | Hip dysplasia (HD) is a frequent cause of hip pain in skeletally mature patients and may lead to osteoarthritis (OA). An accurate and early diagnosis may postpone, reduce or even prevent the onset of OA and ultimately hip arthroplasty at a young age. The overall aim of this study was to assess the reliability of an algorithm, designed to read pelvic anterior-posterior (AP) radiographs and to estimate the agreement between the algorithm and human readers for measuring (i) lateral center edge angle of Wiberg (LCEA) and (ii) Acetabular index angle (AIA). The algorithm was based on deep-learning models developed using a modified U-net architecture and ResNet 34. The newly developed algorithm was found to be highly reliable when identifying the anatomical landmarks used for measuring LCEA and AIA in pelvic radiographs, thus offering highly consistent measurement outputs. The study showed that manual identification of the same landmarks made by five specialist readers were subject to variance and the level of agreement between the algorithm and human readers was consequently poor with mean measured differences from 0.37 to 9.56° for right LCEA measurements. The algorithm displayed the highest agreement with the senior orthopedic surgeon. With further development, the algorithm may be a good alternative to humans when screening for HD. |
format | Online Article Text |
id | pubmed-9689405 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96894052022-11-25 A Deep Learning Algorithm for Radiographic Measurements of the Hip in Adults—A Reliability and Agreement Study Jensen, Janni Graumann, Ole Overgaard, Søren Gerke, Oke Lundemann, Michael Haubro, Martin Haagen Varnum, Claus Bak, Lene Rasmussen, Janne Olsen, Lone B. Rasmussen, Benjamin S. B. Diagnostics (Basel) Article Hip dysplasia (HD) is a frequent cause of hip pain in skeletally mature patients and may lead to osteoarthritis (OA). An accurate and early diagnosis may postpone, reduce or even prevent the onset of OA and ultimately hip arthroplasty at a young age. The overall aim of this study was to assess the reliability of an algorithm, designed to read pelvic anterior-posterior (AP) radiographs and to estimate the agreement between the algorithm and human readers for measuring (i) lateral center edge angle of Wiberg (LCEA) and (ii) Acetabular index angle (AIA). The algorithm was based on deep-learning models developed using a modified U-net architecture and ResNet 34. The newly developed algorithm was found to be highly reliable when identifying the anatomical landmarks used for measuring LCEA and AIA in pelvic radiographs, thus offering highly consistent measurement outputs. The study showed that manual identification of the same landmarks made by five specialist readers were subject to variance and the level of agreement between the algorithm and human readers was consequently poor with mean measured differences from 0.37 to 9.56° for right LCEA measurements. The algorithm displayed the highest agreement with the senior orthopedic surgeon. With further development, the algorithm may be a good alternative to humans when screening for HD. MDPI 2022-10-26 /pmc/articles/PMC9689405/ /pubmed/36359441 http://dx.doi.org/10.3390/diagnostics12112597 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Jensen, Janni Graumann, Ole Overgaard, Søren Gerke, Oke Lundemann, Michael Haubro, Martin Haagen Varnum, Claus Bak, Lene Rasmussen, Janne Olsen, Lone B. Rasmussen, Benjamin S. B. A Deep Learning Algorithm for Radiographic Measurements of the Hip in Adults—A Reliability and Agreement Study |
title | A Deep Learning Algorithm for Radiographic Measurements of the Hip in Adults—A Reliability and Agreement Study |
title_full | A Deep Learning Algorithm for Radiographic Measurements of the Hip in Adults—A Reliability and Agreement Study |
title_fullStr | A Deep Learning Algorithm for Radiographic Measurements of the Hip in Adults—A Reliability and Agreement Study |
title_full_unstemmed | A Deep Learning Algorithm for Radiographic Measurements of the Hip in Adults—A Reliability and Agreement Study |
title_short | A Deep Learning Algorithm for Radiographic Measurements of the Hip in Adults—A Reliability and Agreement Study |
title_sort | deep learning algorithm for radiographic measurements of the hip in adults—a reliability and agreement study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689405/ https://www.ncbi.nlm.nih.gov/pubmed/36359441 http://dx.doi.org/10.3390/diagnostics12112597 |
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