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Effect of a Novel Sugar Blend on Weight and Cardiometabolic Health among Healthy Indian Adults: A Randomized, Open-Label Study

Obesity is one of the major factors contributing to noncommunicable diseases (NCDs), which is associated with a high intake of a sugar-rich diet. Sugar blend (a novel combination of sugar and stevia) has half the calories of sugar with the same sweetness at recommended use and offers better complian...

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Autores principales: Aswathiah, Srinath, Prabhu, Sunil Kumar, Lingaiah, Ramanna, Ramanna, Anusha, Prabhu, Jyothi S., Pankaj, Shashi Kishor, Mehta, Arti, Bapna, Arohi, Raghavan, Govindarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689513/
https://www.ncbi.nlm.nih.gov/pubmed/36429137
http://dx.doi.org/10.3390/foods11223545
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author Aswathiah, Srinath
Prabhu, Sunil Kumar
Lingaiah, Ramanna
Ramanna, Anusha
Prabhu, Jyothi S.
Pankaj, Shashi Kishor
Mehta, Arti
Bapna, Arohi
Raghavan, Govindarajan
author_facet Aswathiah, Srinath
Prabhu, Sunil Kumar
Lingaiah, Ramanna
Ramanna, Anusha
Prabhu, Jyothi S.
Pankaj, Shashi Kishor
Mehta, Arti
Bapna, Arohi
Raghavan, Govindarajan
author_sort Aswathiah, Srinath
collection PubMed
description Obesity is one of the major factors contributing to noncommunicable diseases (NCDs), which is associated with a high intake of a sugar-rich diet. Sugar blend (a novel combination of sugar and stevia) has half the calories of sugar with the same sweetness at recommended use and offers better compliance. A randomized controlled trial was conducted to evaluate the efficacy and safety of this sugar blend in normal to mildly overweight subjects with a body mass index (BMI) of 23–26 kg/m. Sixty subjects were categorized into Group A: Sugar group (n = 30), and Group B: Sugar blend group (n = 30). The primary outcomes evaluated were weight, waist circumference, hip circumference, waist/hip ratio, BMI, and the secondary outcomes evaluated were lipid profile, random blood sugar, and HbA1c. All these parameters were assessed at baseline, 30 days, 60 days, and 90 days. Group B showed a significantly higher weight loss (p = 0.013) at 90 days compared with Group A. A significant reduction in waist circumference (p < 0.0001) by 4.4 cm was noted at 90 days, in addition to reduction in total cholesterol (p < 0.0001), triglyceride (p = 0.006), LDL cholesterol (p = 0.0490), and VLDL cholesterol (p = 0.006) in Group B compared with the baseline. The study revealed that the sugar blend is an effective formulation in reducing weight, anthropometric factors, and other related metabolic parameters. It has been proven to be well tolerated and promotes weight loss when used in conjunction with a daily balanced diet and exercise plan.
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spelling pubmed-96895132022-11-25 Effect of a Novel Sugar Blend on Weight and Cardiometabolic Health among Healthy Indian Adults: A Randomized, Open-Label Study Aswathiah, Srinath Prabhu, Sunil Kumar Lingaiah, Ramanna Ramanna, Anusha Prabhu, Jyothi S. Pankaj, Shashi Kishor Mehta, Arti Bapna, Arohi Raghavan, Govindarajan Foods Article Obesity is one of the major factors contributing to noncommunicable diseases (NCDs), which is associated with a high intake of a sugar-rich diet. Sugar blend (a novel combination of sugar and stevia) has half the calories of sugar with the same sweetness at recommended use and offers better compliance. A randomized controlled trial was conducted to evaluate the efficacy and safety of this sugar blend in normal to mildly overweight subjects with a body mass index (BMI) of 23–26 kg/m. Sixty subjects were categorized into Group A: Sugar group (n = 30), and Group B: Sugar blend group (n = 30). The primary outcomes evaluated were weight, waist circumference, hip circumference, waist/hip ratio, BMI, and the secondary outcomes evaluated were lipid profile, random blood sugar, and HbA1c. All these parameters were assessed at baseline, 30 days, 60 days, and 90 days. Group B showed a significantly higher weight loss (p = 0.013) at 90 days compared with Group A. A significant reduction in waist circumference (p < 0.0001) by 4.4 cm was noted at 90 days, in addition to reduction in total cholesterol (p < 0.0001), triglyceride (p = 0.006), LDL cholesterol (p = 0.0490), and VLDL cholesterol (p = 0.006) in Group B compared with the baseline. The study revealed that the sugar blend is an effective formulation in reducing weight, anthropometric factors, and other related metabolic parameters. It has been proven to be well tolerated and promotes weight loss when used in conjunction with a daily balanced diet and exercise plan. MDPI 2022-11-08 /pmc/articles/PMC9689513/ /pubmed/36429137 http://dx.doi.org/10.3390/foods11223545 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Aswathiah, Srinath
Prabhu, Sunil Kumar
Lingaiah, Ramanna
Ramanna, Anusha
Prabhu, Jyothi S.
Pankaj, Shashi Kishor
Mehta, Arti
Bapna, Arohi
Raghavan, Govindarajan
Effect of a Novel Sugar Blend on Weight and Cardiometabolic Health among Healthy Indian Adults: A Randomized, Open-Label Study
title Effect of a Novel Sugar Blend on Weight and Cardiometabolic Health among Healthy Indian Adults: A Randomized, Open-Label Study
title_full Effect of a Novel Sugar Blend on Weight and Cardiometabolic Health among Healthy Indian Adults: A Randomized, Open-Label Study
title_fullStr Effect of a Novel Sugar Blend on Weight and Cardiometabolic Health among Healthy Indian Adults: A Randomized, Open-Label Study
title_full_unstemmed Effect of a Novel Sugar Blend on Weight and Cardiometabolic Health among Healthy Indian Adults: A Randomized, Open-Label Study
title_short Effect of a Novel Sugar Blend on Weight and Cardiometabolic Health among Healthy Indian Adults: A Randomized, Open-Label Study
title_sort effect of a novel sugar blend on weight and cardiometabolic health among healthy indian adults: a randomized, open-label study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689513/
https://www.ncbi.nlm.nih.gov/pubmed/36429137
http://dx.doi.org/10.3390/foods11223545
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