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Rotationally Adjustable Hyperthermia Applicators: A Computational Comparative Study of Circular and Linear Array Applicators

Microwave breast hyperthermia (MH) aims to increase the temperature at the tumor location with minimal change in the healthy tissue. To this end, the specific absorption rate ([Formula: see text]) inside the breast is optimized. The choice of the MH applicator design is important for a superior ener...

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Autores principales: Yildiz, Gulsah, Yilmaz, Tuba, Akduman, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689518/
https://www.ncbi.nlm.nih.gov/pubmed/36359518
http://dx.doi.org/10.3390/diagnostics12112677
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author Yildiz, Gulsah
Yilmaz, Tuba
Akduman, Ibrahim
author_facet Yildiz, Gulsah
Yilmaz, Tuba
Akduman, Ibrahim
author_sort Yildiz, Gulsah
collection PubMed
description Microwave breast hyperthermia (MH) aims to increase the temperature at the tumor location with minimal change in the healthy tissue. To this end, the specific absorption rate ([Formula: see text]) inside the breast is optimized. The choice of the MH applicator design is important for a superior energy focus on the target. Although hyperthermia treatment planning (HTP) changes for every patient, the MH applicator is required to be effective for different breast models and tumor types. The linear applicator ([Formula: see text]) is one of the previously proposed applicator designs with linearly arranged antennas; however, it suffers from low focusing ability in certain breast regions due to its unsymmetrical geometrical features. In this paper, we propose to radially adjust the [Formula: see text] to obtain alternative excitation schemes without actually changing the applicator. Antipodal Vivaldi antennas were utilized, and the antenna excitations were optimized with particle swarm optimization (PSO). The comparison of the rotated and the fixed linear applicator, between 12-antenna circular and linear applicators, and finally, between a 24-antenna circular applicator are provided. Within the 12 rotation angles and two target locations that were analyzed, the 135° axially rotated linear applicator gave a 35% to 84% higher target-to-breast [Formula: see text] ratio ([Formula: see text]) and a 21% to 28% higher target-to-breast temperature ratio ([Formula: see text]) than the fixed linear applicator. For the deep-seated target, the 135° rotated linear applicator had an 80% higher [Formula: see text] and a 59% higher [Formula: see text] than the 12-antenna circular applicator, while the results were comparable to the 24-antenna circular applicator.
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spelling pubmed-96895182022-11-25 Rotationally Adjustable Hyperthermia Applicators: A Computational Comparative Study of Circular and Linear Array Applicators Yildiz, Gulsah Yilmaz, Tuba Akduman, Ibrahim Diagnostics (Basel) Article Microwave breast hyperthermia (MH) aims to increase the temperature at the tumor location with minimal change in the healthy tissue. To this end, the specific absorption rate ([Formula: see text]) inside the breast is optimized. The choice of the MH applicator design is important for a superior energy focus on the target. Although hyperthermia treatment planning (HTP) changes for every patient, the MH applicator is required to be effective for different breast models and tumor types. The linear applicator ([Formula: see text]) is one of the previously proposed applicator designs with linearly arranged antennas; however, it suffers from low focusing ability in certain breast regions due to its unsymmetrical geometrical features. In this paper, we propose to radially adjust the [Formula: see text] to obtain alternative excitation schemes without actually changing the applicator. Antipodal Vivaldi antennas were utilized, and the antenna excitations were optimized with particle swarm optimization (PSO). The comparison of the rotated and the fixed linear applicator, between 12-antenna circular and linear applicators, and finally, between a 24-antenna circular applicator are provided. Within the 12 rotation angles and two target locations that were analyzed, the 135° axially rotated linear applicator gave a 35% to 84% higher target-to-breast [Formula: see text] ratio ([Formula: see text]) and a 21% to 28% higher target-to-breast temperature ratio ([Formula: see text]) than the fixed linear applicator. For the deep-seated target, the 135° rotated linear applicator had an 80% higher [Formula: see text] and a 59% higher [Formula: see text] than the 12-antenna circular applicator, while the results were comparable to the 24-antenna circular applicator. MDPI 2022-11-03 /pmc/articles/PMC9689518/ /pubmed/36359518 http://dx.doi.org/10.3390/diagnostics12112677 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yildiz, Gulsah
Yilmaz, Tuba
Akduman, Ibrahim
Rotationally Adjustable Hyperthermia Applicators: A Computational Comparative Study of Circular and Linear Array Applicators
title Rotationally Adjustable Hyperthermia Applicators: A Computational Comparative Study of Circular and Linear Array Applicators
title_full Rotationally Adjustable Hyperthermia Applicators: A Computational Comparative Study of Circular and Linear Array Applicators
title_fullStr Rotationally Adjustable Hyperthermia Applicators: A Computational Comparative Study of Circular and Linear Array Applicators
title_full_unstemmed Rotationally Adjustable Hyperthermia Applicators: A Computational Comparative Study of Circular and Linear Array Applicators
title_short Rotationally Adjustable Hyperthermia Applicators: A Computational Comparative Study of Circular and Linear Array Applicators
title_sort rotationally adjustable hyperthermia applicators: a computational comparative study of circular and linear array applicators
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689518/
https://www.ncbi.nlm.nih.gov/pubmed/36359518
http://dx.doi.org/10.3390/diagnostics12112677
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