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RIP140-Mediated NF-κB Inflammatory Pathway Promotes Metabolic Dysregulation in Retinal Pigment Epithelium Cells

Metabolic dysregulation of the retinal pigment epithelium (RPE) has been implicated in age-related macular degeneration (AMD). However, the molecular regulation of RPE metabolism remains unclear. RIP140 is known to affect oxidative metabolism and mitochondrial biogenesis by negatively controlling mi...

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Detalles Bibliográficos
Autores principales: Guo, Zeli, Shen, Yuli, Zhong, Jianwen, Li, Zhuoyun, Guo, Qi, Yao, Xiangchao, Wang, Yandong, Wu, Wenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689634/
https://www.ncbi.nlm.nih.gov/pubmed/36421677
http://dx.doi.org/10.3390/cimb44110393