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Sex and Age Influence on Association of CYP450 Polymorphism with Midazolam Levels in Critically Ill Children

Midazolam is a drug that is metabolized by cytochrome P450 (CYP450) enzymes, particularly CYP3A4 and CYP3A5. The present study aimed to determine the sex and age influence on association of CYP450 polymorphism with midazolam levels in critically ill children. Seventy-two DNA samples were genotyped b...

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Detalles Bibliográficos
Autores principales:	Flores-Pérez, Carmen, Flores-Pérez, Janett, de Jesús Castillejos López, Manuel, Chávez-Pacheco, Juan Luis, Tejada-Gutiérrez, Karla Miroslava, Aquino-Gálvez, Arnoldo, Torres-Espíndola, Luz María
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689687/ https://www.ncbi.nlm.nih.gov/pubmed/36428856 http://dx.doi.org/10.3390/diagnostics12112797

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