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PR3-ANCAs Detected by Third-Generation ELISA Predicts Severe Disease and Poor Survival in Primary Sclerosing Cholangitis

A highly sensitive detection of anti-neutrophil cytoplasmic antibodies to serine proteinase-3 (PR3-ANCAs) aids in the serological diagnosis of autoimmune liver disorders and the prediction of severity in primary sclerosing cholangitis (PSC). Here, we evaluate a novel third-generation ELISA for the d...

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Detalles Bibliográficos
Autores principales: Lopens, Steffi, Wunsch, Ewa, Milkiewicz, Malgorzata, Röber, Nadja, Zarske, Grit, Nasser, Abdullah, Conrad, Karsten, Laass, Martin, Rödiger, Stefan, Krawczyk, Marcin, Roggenbuck, Dirk, Milkiewicz, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689935/
https://www.ncbi.nlm.nih.gov/pubmed/36359524
http://dx.doi.org/10.3390/diagnostics12112682