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Effect of Transcranial Direct Current Stimulation Augmented with Motor Imagery and Upper-Limb Functional Training for Upper-Limb Stroke Rehabilitation: A Prospective Randomized Controlled Trial

Background: Combining transcranial direct current stimulation (tDCS) with other therapies is reported to produce promising results in patients with stroke. The purpose of the study was to determine the effect of combining tDCS with motor imagery (MI) and upper-limb functional training for upper-limb...

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Autores principales: Kashoo, Faizan Zaffar, Al-Baradie, Raid Saleem, Alzahrani, Msaad, Alanazi, Ahmad, Manzar, Md Dilshad, Gugnani, Anchit, Sidiq, Mohammad, Shaphe, Mohammad Abu, Sirajudeen, Mohamed Sherif, Ahmad, Mehrunnisha, Althumayri, Bader, Aljandal, Abdullah, Almansour, Ahmed, Alshewaier, Shady Abdullah, Chahal, Aksh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690138/
https://www.ncbi.nlm.nih.gov/pubmed/36429924
http://dx.doi.org/10.3390/ijerph192215199
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author Kashoo, Faizan Zaffar
Al-Baradie, Raid Saleem
Alzahrani, Msaad
Alanazi, Ahmad
Manzar, Md Dilshad
Gugnani, Anchit
Sidiq, Mohammad
Shaphe, Mohammad Abu
Sirajudeen, Mohamed Sherif
Ahmad, Mehrunnisha
Althumayri, Bader
Aljandal, Abdullah
Almansour, Ahmed
Alshewaier, Shady Abdullah
Chahal, Aksh
author_facet Kashoo, Faizan Zaffar
Al-Baradie, Raid Saleem
Alzahrani, Msaad
Alanazi, Ahmad
Manzar, Md Dilshad
Gugnani, Anchit
Sidiq, Mohammad
Shaphe, Mohammad Abu
Sirajudeen, Mohamed Sherif
Ahmad, Mehrunnisha
Althumayri, Bader
Aljandal, Abdullah
Almansour, Ahmed
Alshewaier, Shady Abdullah
Chahal, Aksh
author_sort Kashoo, Faizan Zaffar
collection PubMed
description Background: Combining transcranial direct current stimulation (tDCS) with other therapies is reported to produce promising results in patients with stroke. The purpose of the study was to determine the effect of combining tDCS with motor imagery (MI) and upper-limb functional training for upper-limb rehabilitation among patients with chronic stroke. Methods: A single-center, prospective, randomized controlled trial was conducted among 64 patients with chronic stroke. The control group received sham tDCS with MI, while the experimental group received real tDCS with MI. Both groups performed five different upper-limb functional training exercises coupled with tDCS for 30 min, five times per week for two weeks. Fugl-Meyer’s scale (FMA) and the Action Research Arm Test (ARAT) were used to measure the outcome measures at baseline and after the completion of the 10th session. Results: Analysis of covariance showed significant improvements in the post-test mean scores for FMA (F (414.4) = 35.79, p < 0.001; η(2) = 0.37) and ARAT (F (440.09) = 37.46, p < 0.001; η(2) = 0.38) in the experimental group compared to the control group while controlling for baseline scores. Conclusions: Anodal tDCS stimulation over the affected primary motor cortex coupled with MI and upper-limb functional training reduces impairment and disability of the upper limbs among patients with chronic stroke.
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spelling pubmed-96901382022-11-25 Effect of Transcranial Direct Current Stimulation Augmented with Motor Imagery and Upper-Limb Functional Training for Upper-Limb Stroke Rehabilitation: A Prospective Randomized Controlled Trial Kashoo, Faizan Zaffar Al-Baradie, Raid Saleem Alzahrani, Msaad Alanazi, Ahmad Manzar, Md Dilshad Gugnani, Anchit Sidiq, Mohammad Shaphe, Mohammad Abu Sirajudeen, Mohamed Sherif Ahmad, Mehrunnisha Althumayri, Bader Aljandal, Abdullah Almansour, Ahmed Alshewaier, Shady Abdullah Chahal, Aksh Int J Environ Res Public Health Article Background: Combining transcranial direct current stimulation (tDCS) with other therapies is reported to produce promising results in patients with stroke. The purpose of the study was to determine the effect of combining tDCS with motor imagery (MI) and upper-limb functional training for upper-limb rehabilitation among patients with chronic stroke. Methods: A single-center, prospective, randomized controlled trial was conducted among 64 patients with chronic stroke. The control group received sham tDCS with MI, while the experimental group received real tDCS with MI. Both groups performed five different upper-limb functional training exercises coupled with tDCS for 30 min, five times per week for two weeks. Fugl-Meyer’s scale (FMA) and the Action Research Arm Test (ARAT) were used to measure the outcome measures at baseline and after the completion of the 10th session. Results: Analysis of covariance showed significant improvements in the post-test mean scores for FMA (F (414.4) = 35.79, p < 0.001; η(2) = 0.37) and ARAT (F (440.09) = 37.46, p < 0.001; η(2) = 0.38) in the experimental group compared to the control group while controlling for baseline scores. Conclusions: Anodal tDCS stimulation over the affected primary motor cortex coupled with MI and upper-limb functional training reduces impairment and disability of the upper limbs among patients with chronic stroke. MDPI 2022-11-17 /pmc/articles/PMC9690138/ /pubmed/36429924 http://dx.doi.org/10.3390/ijerph192215199 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kashoo, Faizan Zaffar
Al-Baradie, Raid Saleem
Alzahrani, Msaad
Alanazi, Ahmad
Manzar, Md Dilshad
Gugnani, Anchit
Sidiq, Mohammad
Shaphe, Mohammad Abu
Sirajudeen, Mohamed Sherif
Ahmad, Mehrunnisha
Althumayri, Bader
Aljandal, Abdullah
Almansour, Ahmed
Alshewaier, Shady Abdullah
Chahal, Aksh
Effect of Transcranial Direct Current Stimulation Augmented with Motor Imagery and Upper-Limb Functional Training for Upper-Limb Stroke Rehabilitation: A Prospective Randomized Controlled Trial
title Effect of Transcranial Direct Current Stimulation Augmented with Motor Imagery and Upper-Limb Functional Training for Upper-Limb Stroke Rehabilitation: A Prospective Randomized Controlled Trial
title_full Effect of Transcranial Direct Current Stimulation Augmented with Motor Imagery and Upper-Limb Functional Training for Upper-Limb Stroke Rehabilitation: A Prospective Randomized Controlled Trial
title_fullStr Effect of Transcranial Direct Current Stimulation Augmented with Motor Imagery and Upper-Limb Functional Training for Upper-Limb Stroke Rehabilitation: A Prospective Randomized Controlled Trial
title_full_unstemmed Effect of Transcranial Direct Current Stimulation Augmented with Motor Imagery and Upper-Limb Functional Training for Upper-Limb Stroke Rehabilitation: A Prospective Randomized Controlled Trial
title_short Effect of Transcranial Direct Current Stimulation Augmented with Motor Imagery and Upper-Limb Functional Training for Upper-Limb Stroke Rehabilitation: A Prospective Randomized Controlled Trial
title_sort effect of transcranial direct current stimulation augmented with motor imagery and upper-limb functional training for upper-limb stroke rehabilitation: a prospective randomized controlled trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690138/
https://www.ncbi.nlm.nih.gov/pubmed/36429924
http://dx.doi.org/10.3390/ijerph192215199
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