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Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools

Background: How different tools for evaluating health-related quality of life (QoL) reflect the burden of vitiligo has rarely been compared. In this study, we aim to evaluate the impact of vitiligo on QoL using currently available tools. Methods: A single-center, cross-sectional study of vitiligo pa...

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Autores principales: Yang, Ting-Ting, Lee, Chien-Hung, Lan, Cheng-Che E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690871/
https://www.ncbi.nlm.nih.gov/pubmed/36429664
http://dx.doi.org/10.3390/ijerph192214943
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author Yang, Ting-Ting
Lee, Chien-Hung
Lan, Cheng-Che E.
author_facet Yang, Ting-Ting
Lee, Chien-Hung
Lan, Cheng-Che E.
author_sort Yang, Ting-Ting
collection PubMed
description Background: How different tools for evaluating health-related quality of life (QoL) reflect the burden of vitiligo has rarely been compared. In this study, we aim to evaluate the impact of vitiligo on QoL using currently available tools. Methods: A single-center, cross-sectional study of vitiligo patients was performed. QoL was evaluated using the dermatology life quality index (DLQI), short form-36 (SF-36), and willingness to pay (WTP). As the original DLQI cutoff score (>10) indicating aginificantly impated QoL was found to underestimate QoL, receiver operating characteristic (ROC) curve was use to determine a new cutoff point discriminating vitiligo patients with positive mental stress (SF-36 mental health ≤ 52). Results: Of the 143 patients enrolled, 24.5% were identified having significant mental stress by SF-36 mental health domain score ≤ 52 while there were only 13.3% patients with significantly hampered QoL indicated by DLQI >10. Using ROC analysis, DLQI ≥ 7 was found to be a more appropriate DLQI cutoff value for identifying mental stress in vitiligo patients. Additionally, the median WTP for treating vitiligo was comparable to other inflammatory skin diseases. Conclusions: There exist discrepancies in the outcomes identifying significant disease burden of vitiligo using DLQI and SF-36, making the current DLQI cutoff score (>10) for identifying significantly affected QoL inappropriate for these patients.
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spelling pubmed-96908712022-11-25 Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools Yang, Ting-Ting Lee, Chien-Hung Lan, Cheng-Che E. Int J Environ Res Public Health Article Background: How different tools for evaluating health-related quality of life (QoL) reflect the burden of vitiligo has rarely been compared. In this study, we aim to evaluate the impact of vitiligo on QoL using currently available tools. Methods: A single-center, cross-sectional study of vitiligo patients was performed. QoL was evaluated using the dermatology life quality index (DLQI), short form-36 (SF-36), and willingness to pay (WTP). As the original DLQI cutoff score (>10) indicating aginificantly impated QoL was found to underestimate QoL, receiver operating characteristic (ROC) curve was use to determine a new cutoff point discriminating vitiligo patients with positive mental stress (SF-36 mental health ≤ 52). Results: Of the 143 patients enrolled, 24.5% were identified having significant mental stress by SF-36 mental health domain score ≤ 52 while there were only 13.3% patients with significantly hampered QoL indicated by DLQI >10. Using ROC analysis, DLQI ≥ 7 was found to be a more appropriate DLQI cutoff value for identifying mental stress in vitiligo patients. Additionally, the median WTP for treating vitiligo was comparable to other inflammatory skin diseases. Conclusions: There exist discrepancies in the outcomes identifying significant disease burden of vitiligo using DLQI and SF-36, making the current DLQI cutoff score (>10) for identifying significantly affected QoL inappropriate for these patients. MDPI 2022-11-13 /pmc/articles/PMC9690871/ /pubmed/36429664 http://dx.doi.org/10.3390/ijerph192214943 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yang, Ting-Ting
Lee, Chien-Hung
Lan, Cheng-Che E.
Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools
title Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools
title_full Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools
title_fullStr Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools
title_full_unstemmed Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools
title_short Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools
title_sort impact of vitiligo on life quality of patients: assessment of currently available tools
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690871/
https://www.ncbi.nlm.nih.gov/pubmed/36429664
http://dx.doi.org/10.3390/ijerph192214943
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