TBPEH-TBPB Initiate the Radical Addition of Benzaldehyde and Allyl Esters

Tert-butylperoxy-2-ethylhexanoate (TBPEH) and tert-butyl peroxybenzoate (TBPB) promote the radical acylation of allyl ester with benzaldehyde to synthesize new carbonyl-containing compounds under solvent-free and metal-free conditions. This reaction is compatible with electron-donating and halogen g...

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Detalles Bibliográficos
Autores principales: Sun, Binlong, Tian, Xiaoyu, Yang, Sen, Wang, Yingying, Shao, Yingying, Fu, Xinhao, Wang, Wenyuan, Tu, Minting, Chen, Yang, Wu, Junhui, Wu, Changyuan, Tan, Chengxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690988/
https://www.ncbi.nlm.nih.gov/pubmed/36430186
http://dx.doi.org/10.3390/ijms232213704
Descripción
Sumario:Tert-butylperoxy-2-ethylhexanoate (TBPEH) and tert-butyl peroxybenzoate (TBPB) promote the radical acylation of allyl ester with benzaldehyde to synthesize new carbonyl-containing compounds under solvent-free and metal-free conditions. This reaction is compatible with electron-donating and halogen groups and has excellent atom utilization and chemical selectivity. Furthermore, the synthetic compounds can further apply to the preparation of lactone, piperidine, tetrazole and oxazole.

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