TBPEH-TBPB Initiate the Radical Addition of Benzaldehyde and Allyl Esters

Tert-butylperoxy-2-ethylhexanoate (TBPEH) and tert-butyl peroxybenzoate (TBPB) promote the radical acylation of allyl ester with benzaldehyde to synthesize new carbonyl-containing compounds under solvent-free and metal-free conditions. This reaction is compatible with electron-donating and halogen g...

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Autores principales: Sun, Binlong, Tian, Xiaoyu, Yang, Sen, Wang, Yingying, Shao, Yingying, Fu, Xinhao, Wang, Wenyuan, Tu, Minting, Chen, Yang, Wu, Junhui, Wu, Changyuan, Tan, Chengxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690988/
https://www.ncbi.nlm.nih.gov/pubmed/36430186
http://dx.doi.org/10.3390/ijms232213704
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author Sun, Binlong
Tian, Xiaoyu
Yang, Sen
Wang, Yingying
Shao, Yingying
Fu, Xinhao
Wang, Wenyuan
Tu, Minting
Chen, Yang
Wu, Junhui
Wu, Changyuan
Tan, Chengxia
author_facet Sun, Binlong
Tian, Xiaoyu
Yang, Sen
Wang, Yingying
Shao, Yingying
Fu, Xinhao
Wang, Wenyuan
Tu, Minting
Chen, Yang
Wu, Junhui
Wu, Changyuan
Tan, Chengxia
author_sort Sun, Binlong
collection PubMed
description Tert-butylperoxy-2-ethylhexanoate (TBPEH) and tert-butyl peroxybenzoate (TBPB) promote the radical acylation of allyl ester with benzaldehyde to synthesize new carbonyl-containing compounds under solvent-free and metal-free conditions. This reaction is compatible with electron-donating and halogen groups and has excellent atom utilization and chemical selectivity. Furthermore, the synthetic compounds can further apply to the preparation of lactone, piperidine, tetrazole and oxazole.
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spelling pubmed-96909882022-11-25 TBPEH-TBPB Initiate the Radical Addition of Benzaldehyde and Allyl Esters Sun, Binlong Tian, Xiaoyu Yang, Sen Wang, Yingying Shao, Yingying Fu, Xinhao Wang, Wenyuan Tu, Minting Chen, Yang Wu, Junhui Wu, Changyuan Tan, Chengxia Int J Mol Sci Article Tert-butylperoxy-2-ethylhexanoate (TBPEH) and tert-butyl peroxybenzoate (TBPB) promote the radical acylation of allyl ester with benzaldehyde to synthesize new carbonyl-containing compounds under solvent-free and metal-free conditions. This reaction is compatible with electron-donating and halogen groups and has excellent atom utilization and chemical selectivity. Furthermore, the synthetic compounds can further apply to the preparation of lactone, piperidine, tetrazole and oxazole. MDPI 2022-11-08 /pmc/articles/PMC9690988/ /pubmed/36430186 http://dx.doi.org/10.3390/ijms232213704 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sun, Binlong
Tian, Xiaoyu
Yang, Sen
Wang, Yingying
Shao, Yingying
Fu, Xinhao
Wang, Wenyuan
Tu, Minting
Chen, Yang
Wu, Junhui
Wu, Changyuan
Tan, Chengxia
TBPEH-TBPB Initiate the Radical Addition of Benzaldehyde and Allyl Esters
title TBPEH-TBPB Initiate the Radical Addition of Benzaldehyde and Allyl Esters
title_full TBPEH-TBPB Initiate the Radical Addition of Benzaldehyde and Allyl Esters
title_fullStr TBPEH-TBPB Initiate the Radical Addition of Benzaldehyde and Allyl Esters
title_full_unstemmed TBPEH-TBPB Initiate the Radical Addition of Benzaldehyde and Allyl Esters
title_short TBPEH-TBPB Initiate the Radical Addition of Benzaldehyde and Allyl Esters
title_sort tbpeh-tbpb initiate the radical addition of benzaldehyde and allyl esters
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690988/
https://www.ncbi.nlm.nih.gov/pubmed/36430186
http://dx.doi.org/10.3390/ijms232213704
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