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Hippocalcin-Like 1 blunts liver lipid metabolism to suppress tumorigenesis via directly targeting RUVBL1-mTOR signaling
Rationale: Hepatocellular carcinoma (HCC) is one of the most severe cancers worldwide, with few effective targeted therapies for HCC. Lipid metabolic reprogramming is emerged as a hallmark of cancer metabolism that guides response to antitumoral therapies. Such lipid metabolic alteration in cancers...
Autores principales: | Chen, Tao, Yuan, Zhiqing, Lei, Zhou, Duan, Jinlin, Xue, Junyan, Lu, Ting, Yan, Guouan, Zhang, Lei, Liu, Yanfeng, Li, Qiwei, Zhang, Yonglong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691343/ https://www.ncbi.nlm.nih.gov/pubmed/36438486 http://dx.doi.org/10.7150/thno.75936 |
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