Modulating the pharmacokinetic profile of Actinium-225-labeled macropa-derived radioconjugates by dual targeting of PSMA and albumin

Rationale: Small (225)Ac-labeled prostate-specific membrane antigen (PSMA)-targeted radioconjugates have been described for targeted alpha therapy of metastatic castration-resistant prostate cancer. Transient binding to serum albumin as a highly abundant, inherent transport protein represents a comm...

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Detalles Bibliográficos
Autores principales: Reissig, Falco, Zarschler, Kristof, Novy, Zbynek, Petrik, Milos, Bendova, Katerina, Kurfurstova, Daniela, Bouchal, Jan, Ludik, Marie-Charlotte, Brandt, Florian, Kopka, Klaus, Khoylou, Marta, Pietzsch, Hans-Jürgen, Hajduch, Marian, Mamat, Constantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691366/
https://www.ncbi.nlm.nih.gov/pubmed/36438496
http://dx.doi.org/10.7150/thno.78043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691366/
https://www.ncbi.nlm.nih.gov/pubmed/36438496
http://dx.doi.org/10.7150/thno.78043

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