The BRD4 Inhibitor dBET57 Exerts Anticancer Effects by Targeting Superenhancer-Related Genes in Neuroblastoma

Neuroblastoma (NB) is the most common solid tumor of the neural crest cell origin in children and has a poor prognosis in high-risk patients. The oncogene MYCN was found to be amplified at extremely high levels in approximately 20% of neuroblastoma cases. In recent years, research on the targeted hy...

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Detalles Bibliográficos
Autores principales: Jia, Si-Qi, Zhuo, Ran, Zhang, Zi-Mu, Yang, Yang, Tao, Yan-Fang, Wang, Jian-Wei, Li, Xiao-Lu, Xie, Yi, Li, Gen, Wu, Di, Chen, Yan-Ling, Yu, Juan-Juan, Feng, Chen-xi, Li, Zhi-Heng, Zhou, Rong-Fang, Yang, Ran-Dong, Yang, Peng-Cheng, Zhou, Bi, Wan, Xiao-Mei, Wu, Yu-Meng, Jiao, Wan-Yan, Zhou, Ni-Na, Fang, Fang, Pan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691391/
https://www.ncbi.nlm.nih.gov/pubmed/36438198
http://dx.doi.org/10.1155/2022/7945884

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