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Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review

PURPOSE: This scoping review aims to identify and describe knowledge gaps and research priorities in veno-arterial extracorporeal membrane oxygenation (VA-ECMO). METHODS: An expert panel was recruited consisting of eight international experts from different backgrounds. First, a list of priority top...

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Autores principales: Raasveld, Senta Jorinde, Volleman, Carolien, Combes, Alain, Broman, Lars Mikael, Taccone, Fabio Silvio, Peters, Elma, ten Berg, Sanne, van den Brom, Charissa E., Thiele, Holger, Lorusso, Roberto, Henriques, José P. S., Vlaar, Alexander P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691798/
https://www.ncbi.nlm.nih.gov/pubmed/36424482
http://dx.doi.org/10.1186/s40635-022-00478-z
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author Raasveld, Senta Jorinde
Volleman, Carolien
Combes, Alain
Broman, Lars Mikael
Taccone, Fabio Silvio
Peters, Elma
ten Berg, Sanne
van den Brom, Charissa E.
Thiele, Holger
Lorusso, Roberto
Henriques, José P. S.
Vlaar, Alexander P. J.
author_facet Raasveld, Senta Jorinde
Volleman, Carolien
Combes, Alain
Broman, Lars Mikael
Taccone, Fabio Silvio
Peters, Elma
ten Berg, Sanne
van den Brom, Charissa E.
Thiele, Holger
Lorusso, Roberto
Henriques, José P. S.
Vlaar, Alexander P. J.
author_sort Raasveld, Senta Jorinde
collection PubMed
description PURPOSE: This scoping review aims to identify and describe knowledge gaps and research priorities in veno-arterial extracorporeal membrane oxygenation (VA-ECMO). METHODS: An expert panel was recruited consisting of eight international experts from different backgrounds. First, a list of priority topics was made. Second, the panel developed structured questions using population, intervention, comparison and outcomes (PICO) format. All PICOs were scored and prioritized. For every selected PICO, a structured literature search was performed. RESULTS: After an initial list of 49 topics, eight were scored as high-priority. For most of these selected topics, current literature is limited to observational studies, mainly consisting of retrospective cohorts. Only for ECPR and anticoagulation, randomized controlled trials (RCTs) have been performed or are ongoing. Per topic, a summary of the literature is stated including recommendations for further research. CONCLUSIONS: This scoping review identifies and presents an overview of knowledge gaps and research priorities in VA-ECMO. Current literature is mostly limited to observational studies, although with increasing attention for this patient population, more RCTs are finishing or ongoing. Translational research, from preclinical trials to high-quality or randomized controlled trials, is important to improve the standard practices in this critically ill patient population. Take-home message This scoping review identifies and presents an overview of research gaps and priorities in VA-ECMO. Translational research, from preclinical trials to high-quality or randomized controlled trials, is important to improve the standard practices in this critically ill patient population. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40635-022-00478-z.
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spelling pubmed-96917982022-11-26 Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review Raasveld, Senta Jorinde Volleman, Carolien Combes, Alain Broman, Lars Mikael Taccone, Fabio Silvio Peters, Elma ten Berg, Sanne van den Brom, Charissa E. Thiele, Holger Lorusso, Roberto Henriques, José P. S. Vlaar, Alexander P. J. Intensive Care Med Exp Reviews PURPOSE: This scoping review aims to identify and describe knowledge gaps and research priorities in veno-arterial extracorporeal membrane oxygenation (VA-ECMO). METHODS: An expert panel was recruited consisting of eight international experts from different backgrounds. First, a list of priority topics was made. Second, the panel developed structured questions using population, intervention, comparison and outcomes (PICO) format. All PICOs were scored and prioritized. For every selected PICO, a structured literature search was performed. RESULTS: After an initial list of 49 topics, eight were scored as high-priority. For most of these selected topics, current literature is limited to observational studies, mainly consisting of retrospective cohorts. Only for ECPR and anticoagulation, randomized controlled trials (RCTs) have been performed or are ongoing. Per topic, a summary of the literature is stated including recommendations for further research. CONCLUSIONS: This scoping review identifies and presents an overview of knowledge gaps and research priorities in VA-ECMO. Current literature is mostly limited to observational studies, although with increasing attention for this patient population, more RCTs are finishing or ongoing. Translational research, from preclinical trials to high-quality or randomized controlled trials, is important to improve the standard practices in this critically ill patient population. Take-home message This scoping review identifies and presents an overview of research gaps and priorities in VA-ECMO. Translational research, from preclinical trials to high-quality or randomized controlled trials, is important to improve the standard practices in this critically ill patient population. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40635-022-00478-z. Springer International Publishing 2022-11-25 /pmc/articles/PMC9691798/ /pubmed/36424482 http://dx.doi.org/10.1186/s40635-022-00478-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Reviews
Raasveld, Senta Jorinde
Volleman, Carolien
Combes, Alain
Broman, Lars Mikael
Taccone, Fabio Silvio
Peters, Elma
ten Berg, Sanne
van den Brom, Charissa E.
Thiele, Holger
Lorusso, Roberto
Henriques, José P. S.
Vlaar, Alexander P. J.
Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review
title Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review
title_full Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review
title_fullStr Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review
title_full_unstemmed Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review
title_short Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review
title_sort knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691798/
https://www.ncbi.nlm.nih.gov/pubmed/36424482
http://dx.doi.org/10.1186/s40635-022-00478-z
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