Enhancing the BOADICEA cancer risk prediction model to incorporate new data on RAD51C, RAD51D, BARD1 updates to tumour pathology and cancer incidence

BACKGROUND: BOADICEA (Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm) for breast cancer and the epithelial tubo-ovarian cancer (EOC) models included in the CanRisk tool (www.canrisk.org) provide future cancer risks based on pathogenic variants in cancer-susceptibil...

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Detalles Bibliográficos
Autores principales: Lee, Andrew, Mavaddat, Nasim, Cunningham, Alex, Carver, Tim, Ficorella, Lorenzo, Archer, Stephanie, Walter, Fiona M, Tischkowitz, Marc, Roberts, Jonathan, Usher-Smith, Juliet, Simard, Jacques, Schmidt, Marjanka K, Devilee, Peter, Zadnik, Vesna, Jürgens, Hannes, Mouret-Fourme, Emmanuelle, De Pauw, Antoine, Rookus, Matti, Mooij, Thea M, Pharoah, Paul PD, Easton, Douglas F, Antoniou, Antonis C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Cancer Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691826/
https://www.ncbi.nlm.nih.gov/pubmed/36162851
http://dx.doi.org/10.1136/jmedgenet-2022-108471

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