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A joint transcriptional regulatory network and protein activity inference analysis identifies clinically associated master regulators for biliary atresia

Biliary atresia (BA) is a devastating cholangiopathy in neonate. Transcription factors (TFs), a type of master regulators in biological processes and diseases, have been implicated in pathogenesis of BA. However, a global view of TFs and how they link to clinical presentations remain explored. Here,...

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Detalles Bibliográficos
Autores principales: Sun, Panpan, Xiao, Manhuan, Chen, Huadong, Zhong, Zhihai, Jiang, Hong, Feng, Xuyang, Luo, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691841/
https://www.ncbi.nlm.nih.gov/pubmed/36440333
http://dx.doi.org/10.3389/fped.2022.1050326