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Activation of astrocyte Gq pathway in hippocampal CA1 region attenuates anesthesia/surgery induced cognitive dysfunction in aged mice

The elderly are particularly vulnerable to brain dysfunction after fracture surgery, but the mechanism underlying the cognitive decline due to anesthesia/surgery is not well understood. In this study, we observed hippocampus-dependent cognitive impairment in aged mice undergoing anesthesia and tibia...

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Detalles Bibliográficos
Autores principales:	Wang, Xupeng, Li, Yanan, Zhao, Juan, Yu, Jiaxu, Zhang, Qi, Xu, Fang, Zhang, Yahui, Zhou, Qi, Yin, Chunping, Hou, Zhiyong, Wang, Qiujun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692004/ https://www.ncbi.nlm.nih.gov/pubmed/36437995 http://dx.doi.org/10.3389/fnagi.2022.1040569

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