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Osimertinib and Bevacizumab Cotreatment for Untreated EGFR-Mutated NSCLC With Malignant Pleural or Pericardial Effusion (SPIRAL II): A Single-Arm, Open-Label, Phase 2 Clinical Trial
INTRODUCTION: First-line treatment of EGFR-mutated NSCLC with erlotinib plus antiangiogenic inhibitor exhibits promising results. However, the efficacy of this combination has not been fully investigated. Therefore, we evaluated the efficacy and safety of osimertinib plus bevacizumab in patients wit...
Autores principales: | Hibino, Makoto, Hiranuma, Osamu, Takemura, Yoshizumi, Katayama, Yuki, Chihara, Yusuke, Harada, Taishi, Fujita, Kohei, Kita, Toshiyuki, Tamiya, Nobuyo, Tsuda, Takeshi, Shiotsu, Shinsuke, Tamura, Yukihiro, Aoyama, Takashi, Nakamura, Yoichi, Terashima, Masaaki, Morimoto, Yoshie, Nagata, Kazuhiro, Yoshimura, Kenichi, Uchino, Junji, Takayama, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692038/ https://www.ncbi.nlm.nih.gov/pubmed/36438852 http://dx.doi.org/10.1016/j.jtocrr.2022.100424 |
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