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Short-term hypoxia triggers ROS and SAFB mediated nuclear matrix and mRNA splicing remodeling
The cellular response to hypoxia, in addition to HIF-dependent transcriptional reprogramming, also involves less characterized transcription-independent processes, such as alternative splicing of the VEGFA transcript leading to the production of the proangiogenic VEGF form. We now show that this eve...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692040/ https://www.ncbi.nlm.nih.gov/pubmed/36427398 http://dx.doi.org/10.1016/j.redox.2022.102545 |