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Short-term hypoxia triggers ROS and SAFB mediated nuclear matrix and mRNA splicing remodeling

The cellular response to hypoxia, in addition to HIF-dependent transcriptional reprogramming, also involves less characterized transcription-independent processes, such as alternative splicing of the VEGFA transcript leading to the production of the proangiogenic VEGF form. We now show that this eve...

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Detalles Bibliográficos
Autores principales: Taze, Chrysa, Drakouli, Sotiria, Samiotaki, Martina, Panayotou, George, Simos, George, Georgatsou, Eleni, Mylonis, Ilias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692040/
https://www.ncbi.nlm.nih.gov/pubmed/36427398
http://dx.doi.org/10.1016/j.redox.2022.102545