Cargando…
Short-term hypoxia triggers ROS and SAFB mediated nuclear matrix and mRNA splicing remodeling
The cellular response to hypoxia, in addition to HIF-dependent transcriptional reprogramming, also involves less characterized transcription-independent processes, such as alternative splicing of the VEGFA transcript leading to the production of the proangiogenic VEGF form. We now show that this eve...
Autores principales: | Taze, Chrysa, Drakouli, Sotiria, Samiotaki, Martina, Panayotou, George, Simos, George, Georgatsou, Eleni, Mylonis, Ilias |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692040/ https://www.ncbi.nlm.nih.gov/pubmed/36427398 http://dx.doi.org/10.1016/j.redox.2022.102545 |
Ejemplares similares
-
ERK signaling controls productive HIF‐1 binding to chromatin and cancer cell adaptation to hypoxia through HIF‐1α interaction with NPM1
por: Koukoulas, Kreon, et al.
Publicado: (2021) -
Hypoxia-Inducible Factors and the Regulation of Lipid Metabolism
por: Mylonis, Ilias, et al.
Publicado: (2019) -
Hypoxia Induces Pro-Fibrotic and Fibrosis Marker Genes in Hepatocellular Carcinoma Cells Independently of Inflammatory Stimulation and the NF-κΒ Pathway
por: Triantafyllou, Eleni-Anastasia, et al.
Publicado: (2019) -
Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1
por: Jiang, Shiming, et al.
Publicado: (2015) -
Specific Inhibition of HIF Activity: Can Peptides Lead the Way?
por: Mylonis, Ilias, et al.
Publicado: (2021)