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Grk7 but not Grk1 undergoes cAMP-dependent phosphorylation in zebrafish cone photoreceptors and mediates cone photoresponse recovery to elevated cAMP
In the vertebrate retina, phosphorylation of photoactivated visual pigments in rods and cones by G protein–coupled receptor kinases (GRKs) is essential for sustained visual function. Previous in vitro analysis demonstrated that GRK1 and GRK7 are phosphorylated by PKA, resulting in a reduced capacity...
Autores principales: | Chrispell, Jared D., Xiong, Yubin, Weiss, Ellen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692042/ https://www.ncbi.nlm.nih.gov/pubmed/36273582 http://dx.doi.org/10.1016/j.jbc.2022.102636 |
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