Methyltransferase SMYD3 impairs hypoxia tolerance by augmenting hypoxia signaling independent of its enzymatic activity

Hypoxia-inducible factor (HIF)1α, a main transcriptional regulator of the cellular response to hypoxia, also plays important roles in oxygen homeostasis of aerobic organisms, which is regulated by multiple mechanisms. However, the full cellular response to hypoxia has not been elucidated. In this st...

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Detalles Bibliográficos
Autores principales: Wang, Zixuan, Chen, Xiaoyun, Fan, Sijia, Zhu, Chunchun, Deng, Hongyan, Tang, Jinhua, Sun, Xueyi, Jia, Shuke, Liao, Qian, Xiao, Wuhan, Liu, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692045/
https://www.ncbi.nlm.nih.gov/pubmed/36273580
http://dx.doi.org/10.1016/j.jbc.2022.102633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692045/
https://www.ncbi.nlm.nih.gov/pubmed/36273580
http://dx.doi.org/10.1016/j.jbc.2022.102633

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