Top-down and bottom-up propagation of disease in the neuronal ceroid lipofuscinoses

BACKGROUND: The Neuronal Ceroid Lipofuscinoses (NCLs) may be considered distinct neurodegenerative disorders with separate underlying molecular causes resulting from monogenetic mutations. An alternative hypothesis is to consider the NCLs as related diseases that share lipofuscin pathobiology as the...

Descripción completa

Detalles Bibliográficos
Autores principales: Ostergaard, John R., Nelvagal, Hemanth R., Cooper, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692088/
https://www.ncbi.nlm.nih.gov/pubmed/36438942
http://dx.doi.org/10.3389/fneur.2022.1061363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692088/
https://www.ncbi.nlm.nih.gov/pubmed/36438942
http://dx.doi.org/10.3389/fneur.2022.1061363

Ejemplares similares