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Polygenic risk scores: An overview from bench to bedside for personalised medicine

Since the first polygenic risk score (PRS) in 2007, research in this area has progressed significantly. The increasing number of SNPs that have been identified by large scale GWAS analyses has fuelled the development of a myriad of PRSs for a wide variety of diseases and, more recently, to PRSs that...

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Detalles Bibliográficos
Autores principales: Cross, Benjamin, Turner, Richard, Pirmohamed, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692112/
https://www.ncbi.nlm.nih.gov/pubmed/36437929
http://dx.doi.org/10.3389/fgene.2022.1000667