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Design of novel disturbing peptides against ACE2 SARS-CoV-2 spike-binding region by computational approaches
The SARS-CoV-2, the virus which is responsible for COVID-19 disease, employs its spike protein to recognize its receptor, angiotensin-converting enzyme 2 (ACE2), and subsequently enters the host cell. In this process, the receptor-binding domain (RBD) of the spike has an interface with the α1-helix...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692113/ https://www.ncbi.nlm.nih.gov/pubmed/36438825 http://dx.doi.org/10.3389/fphar.2022.996005 |