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Design of novel disturbing peptides against ACE2 SARS-CoV-2 spike-binding region by computational approaches

The SARS-CoV-2, the virus which is responsible for COVID-19 disease, employs its spike protein to recognize its receptor, angiotensin-converting enzyme 2 (ACE2), and subsequently enters the host cell. In this process, the receptor-binding domain (RBD) of the spike has an interface with the α1-helix...

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Detalles Bibliográficos
Autores principales: Zareei, Sara, Pourmand, Saeed, Amanlou, Massoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692113/
https://www.ncbi.nlm.nih.gov/pubmed/36438825
http://dx.doi.org/10.3389/fphar.2022.996005

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