Cargando…

Simvastatin Attenuated Tumor Growth in Different Pancreatic Tumor Animal Models

Newly diagnosed pancreatic cancer increases year by year, while the prognosis of pancreatic cancer has not been very good. Statin drugs were found to have protective effects against a variety of cancers, but their association with pancreatic cancer remains to be clarified. This study used different...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Chao-Yi, Yang, Yi-Feng, Wang, Paul C., Shan, Liang, Lin, Stephen, Chen, Po-Jung, Chen, Yi-Jung, Chiang, Han-Sun, Lin, Jaw-Town, Hung, Chi-Feng, Liang, Yao-Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692350/ https://www.ncbi.nlm.nih.gov/pubmed/36422538 http://dx.doi.org/10.3390/ph15111408

Ejemplares similares

Low accuracy of chromogranin A for diagnosing early-stage pancreatic neuroendocrine tumors
por: Tseng, Chao-Ming, et al.
Publicado: (2018)

Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1
por: Lin, Chih-Pei, et al.
Publicado: (2015)

Correction: Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1
por: Lin, Chih-Pei, et al.
Publicado: (2016)

CXCR4 Expression Predicts Early Liver Recurrence and Poor Survival After Resection of Pancreatic Adenocarcinoma
por: Liao, Wei-Chih, et al.
Publicado: (2012)

Deciphering Genetic Alterations of Taiwanese Patients with Pancreatic Adenocarcinoma through Targeted Sequencing
por: Huang, Chi-Cheng, et al.
Publicado: (2022)

Simvastatin Attenuates Cardiac Fibrosis via Regulation of Cardiomyocyte-Derived Exosome Secretion
por: Kuo, Hsuan-Fu, et al.
Publicado: (2019)

Simvastatin–Ezetimibe enhances growth factor expression and attenuates neuron loss in the hippocampus in a model of intracerebral hemorrhage
por: Wang, Kuo‐Wei, et al.
Publicado: (2021)

Endoscopic ultrasound-guided fine-needle biopsy as a tool for studying the intra-tumoral microbiome in pancreatic ductal adenocarcinoma: a pilot study
por: Chu, Chia-Sheng, et al.
Publicado: (2022)

Genes involved in angiogenesis and mTOR pathways are frequently mutated in Asian patients with pancreatic neuroendocrine tumors
por: Chou, Wen-Chi, et al.
Publicado: (2016)

Preclinical Activity of Simvastatin Induces Cell Cycle Arrest in G1 via Blockade of Cyclin D-Cdk4 Expression in Non-Small Cell Lung Cancer (NSCLC)
por: Liang, Yu-Wei, et al.
Publicado: (2013)

Interaction between Tumor-Associated Dendritic Cells and Colon Cancer Cells Contributes to Tumor Progression via CXCL1
por: Hsu, Ya-Ling, et al.
Publicado: (2018)

Glucagon-like peptide receptor agonists attenuate advanced glycation end products-induced inflammation in rat mesangial cells
por: Chang, Jui-Ting, et al.
Publicado: (2017)

Development of Stereo NIR-II Fluorescence Imaging System for 3D Tumor Vasculature in Small Animals
por: Su, Shih-Po, et al.
Publicado: (2022)

Correction: Glucagon-like peptide receptor agonists attenuate advanced glycation end products-induced inflammation in rat mesangial cells
por: Chang, Jui-Ting, et al.
Publicado: (2023)

Simvastatin Combined with Antioxidant Attenuates the Cerebral Vascular Endothelial Inflammatory Response in a Rat Traumatic Brain Injury
por: Wang, Kuo-Wei, et al.
Publicado: (2014)

Realization of NIR-II 3D whole-body contour and tumor blood vessels imaging in small animals using rotational stereo vision technique
por: Su, Shih-Po, et al.
Publicado: (2023)

Pancreatic Fibrosis (Early Chronic Pancreatitis) as Emerging Diagnosis in Structural Causes of Dyspepsia: Evidence from Endoscopic Ultrasonography and Shear Wave Elastography
por: Huang, Chung-Tsui, et al.
Publicado: (2021)

Eradicating gastric cancer
por: Lin, Jaw‐Town, et al.
Publicado: (2017)

Inhibition of hypoxia inducible factor-1α attenuates abdominal aortic aneurysm progression through the down-regulation of matrix metalloproteinases
por: Tsai, Shih-Hung, et al.
Publicado: (2016)

Simvastatin attenuates radiation-induced salivary gland dysfunction in mice
por: Xu, Liping, et al.
Publicado: (2016)

Concordance of Targeted Sequencing from Circulating Tumor DNA and Paired Tumor Tissue for Early Breast Cancer
por: Huang, Chi-Cheng, et al.
Publicado: (2023)

Endocan expression is correlated with poor progression-free survival in patients with pancreatic neuroendocrine tumors
por: Lin, Liang-Yu, et al.
Publicado: (2017)

Simvastatin-induced cell cycle arrest through inhibition of STAT3/SKP2 axis and activation of AMPK to promote p27 and p21 accumulation in hepatocellular carcinoma cells
por: Wang, Sin-Ting, et al.
Publicado: (2017)

c‐Myc promotes lymphatic metastasis of pancreatic neuroendocrine tumor through VEGFC upregulation
por: Chang, Tsung‐Ming, et al.
Publicado: (2020)

PTEN regulates invasiveness in pancreatic neuroendocrine tumors through DUSP19-mediated VEGFR3 dephosphorylation
por: Chang, Tsung-Ming, et al.
Publicado: (2022)

The regulatory role of aberrant Phosphatase and Tensin Homologue and Liver Kinase B1 on AKT/mTOR/c-Myc axis in pancreatic neuroendocrine tumors
por: Chang, Tsung-Ming, et al.
Publicado: (2017)

Percutaneous Computed Tomography-Guided Coaxial Core Biopsy for the Diagnosis of Pancreatic Tumors
por: Su, Yung-Yeh, et al.
Publicado: (2019)

Dextromethorphan Attenuates Sensorineural Hearing Loss in an Animal Model and Population-Based Cohort Study
por: Chen, Hsin-Chien, et al.
Publicado: (2020)

Overexpression of Kynurenine 3-Monooxygenase Correlates with Cancer Malignancy and Predicts Poor Prognosis in Canine Mammary Gland Tumors
por: Chiu, Yi-Han, et al.
Publicado: (2019)

Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) regulates the cell metabolism of pancreatic neuroendocrine tumors (pNET) and de-sensitizes pNET to mTOR inhibitors
por: Chu, Pei-Yi, et al.
Publicado: (2017)

Diagnostic rate of germline pathogenic variants in pancreatic ductal adenocarcinoma patients using whole genome sequencing
por: Chung, An-Ko, et al.
Publicado: (2023)

Simvastatin attenuates tibial bone loss in rats with type 1 diabetes and periodontitis
por: Kim, Ae Ri, et al.
Publicado: (2018)

Simvastatin Attenuates Areca Nut Extract-Induced Subdermal Fibrosis in Mice by Targeting TGF-β Signaling Pathways
por: Chang, Chi-Hua, et al.
Publicado: (2023)

Specific drug delivery efficiently induced human breast tumor regression using a lipoplex by non-covalent association with anti-tumor antibodies
por: Lin, Yu-Ling, et al.
Publicado: (2019)

The protective effect of simvastatin against ultraviolet B-induced corneal endothelial cell death
por: Ho, Yi-Ru, et al.
Publicado: (2018)

MRI features of pediatric atypical teratoid rhabdoid tumors and medulloblastomas of the posterior fossa
por: Wu, Hsin‐Wei, et al.
Publicado: (2023)

Risk factors related to age at diagnosis of pancreatic cancer: a retrospective cohort pilot study
por: Lin, Ro-Ting, et al.
Publicado: (2022)

Aqueous Extract of Kan-Lu-Hsiao-Tu-Tan Ameliorates Collagen-Induced Arthritis in Mice by Inhibiting Oxidative Stress and Inflammatory Responses
por: Chiang, Chih-Chao, et al.
Publicado: (2020)

Traditional Chinese medicine attenuates hospitalization and mortality risks in diabetic patients with carcinoma in situ in Taiwan
por: Tsai, Li-Jen, et al.
Publicado: (2022)

Health-related Quality of Life in Adult Patients with Morbid Obesity Coming for Bariatric Surgery
por: Chang, Chi-Yang, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_dvrto5eunknjr5o4entfq3edi6