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Going Viral—RSV as the Neglected Adult Respiratory Virus

Human respiratory syncytial virus (RSV) is increasingly recognized as a significant viral pathogen in adults with acute respiratory illness, particularly in the elderly, the immunocompromised, and those with underlying cardiopulmonary disease. Although long acknowledged as one of the most common cau...

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Detalles Bibliográficos
Autores principales: Busack, Bethany, Shorr, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692430/
https://www.ncbi.nlm.nih.gov/pubmed/36422576
http://dx.doi.org/10.3390/pathogens11111324
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author Busack, Bethany
Shorr, Andrew F.
author_facet Busack, Bethany
Shorr, Andrew F.
author_sort Busack, Bethany
collection PubMed
description Human respiratory syncytial virus (RSV) is increasingly recognized as a significant viral pathogen in adults with acute respiratory illness, particularly in the elderly, the immunocompromised, and those with underlying cardiopulmonary disease. Although long acknowledged as one of the most common causes of upper respiratory tract infections (URI) in children since its discovery in 1956, the true burden of disease in adults is likely significantly under-recognized. The emerging evidence of RSV as a driver of morbidity and mortality in elderly and immunocompromised patients has sparked advances in vaccine development and renewed interest in quantifying the true burden of disease. This review attempts to summarize the findings of the most recent evidence investigating the burden of RSV related disease in adults and to highlight where future research is needed.
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spelling pubmed-96924302022-11-26 Going Viral—RSV as the Neglected Adult Respiratory Virus Busack, Bethany Shorr, Andrew F. Pathogens Review Human respiratory syncytial virus (RSV) is increasingly recognized as a significant viral pathogen in adults with acute respiratory illness, particularly in the elderly, the immunocompromised, and those with underlying cardiopulmonary disease. Although long acknowledged as one of the most common causes of upper respiratory tract infections (URI) in children since its discovery in 1956, the true burden of disease in adults is likely significantly under-recognized. The emerging evidence of RSV as a driver of morbidity and mortality in elderly and immunocompromised patients has sparked advances in vaccine development and renewed interest in quantifying the true burden of disease. This review attempts to summarize the findings of the most recent evidence investigating the burden of RSV related disease in adults and to highlight where future research is needed. MDPI 2022-11-11 /pmc/articles/PMC9692430/ /pubmed/36422576 http://dx.doi.org/10.3390/pathogens11111324 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Busack, Bethany
Shorr, Andrew F.
Going Viral—RSV as the Neglected Adult Respiratory Virus
title Going Viral—RSV as the Neglected Adult Respiratory Virus
title_full Going Viral—RSV as the Neglected Adult Respiratory Virus
title_fullStr Going Viral—RSV as the Neglected Adult Respiratory Virus
title_full_unstemmed Going Viral—RSV as the Neglected Adult Respiratory Virus
title_short Going Viral—RSV as the Neglected Adult Respiratory Virus
title_sort going viral—rsv as the neglected adult respiratory virus
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692430/
https://www.ncbi.nlm.nih.gov/pubmed/36422576
http://dx.doi.org/10.3390/pathogens11111324
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