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Going Viral—RSV as the Neglected Adult Respiratory Virus
Human respiratory syncytial virus (RSV) is increasingly recognized as a significant viral pathogen in adults with acute respiratory illness, particularly in the elderly, the immunocompromised, and those with underlying cardiopulmonary disease. Although long acknowledged as one of the most common cau...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692430/ https://www.ncbi.nlm.nih.gov/pubmed/36422576 http://dx.doi.org/10.3390/pathogens11111324 |
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author | Busack, Bethany Shorr, Andrew F. |
author_facet | Busack, Bethany Shorr, Andrew F. |
author_sort | Busack, Bethany |
collection | PubMed |
description | Human respiratory syncytial virus (RSV) is increasingly recognized as a significant viral pathogen in adults with acute respiratory illness, particularly in the elderly, the immunocompromised, and those with underlying cardiopulmonary disease. Although long acknowledged as one of the most common causes of upper respiratory tract infections (URI) in children since its discovery in 1956, the true burden of disease in adults is likely significantly under-recognized. The emerging evidence of RSV as a driver of morbidity and mortality in elderly and immunocompromised patients has sparked advances in vaccine development and renewed interest in quantifying the true burden of disease. This review attempts to summarize the findings of the most recent evidence investigating the burden of RSV related disease in adults and to highlight where future research is needed. |
format | Online Article Text |
id | pubmed-9692430 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96924302022-11-26 Going Viral—RSV as the Neglected Adult Respiratory Virus Busack, Bethany Shorr, Andrew F. Pathogens Review Human respiratory syncytial virus (RSV) is increasingly recognized as a significant viral pathogen in adults with acute respiratory illness, particularly in the elderly, the immunocompromised, and those with underlying cardiopulmonary disease. Although long acknowledged as one of the most common causes of upper respiratory tract infections (URI) in children since its discovery in 1956, the true burden of disease in adults is likely significantly under-recognized. The emerging evidence of RSV as a driver of morbidity and mortality in elderly and immunocompromised patients has sparked advances in vaccine development and renewed interest in quantifying the true burden of disease. This review attempts to summarize the findings of the most recent evidence investigating the burden of RSV related disease in adults and to highlight where future research is needed. MDPI 2022-11-11 /pmc/articles/PMC9692430/ /pubmed/36422576 http://dx.doi.org/10.3390/pathogens11111324 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Busack, Bethany Shorr, Andrew F. Going Viral—RSV as the Neglected Adult Respiratory Virus |
title | Going Viral—RSV as the Neglected Adult Respiratory Virus |
title_full | Going Viral—RSV as the Neglected Adult Respiratory Virus |
title_fullStr | Going Viral—RSV as the Neglected Adult Respiratory Virus |
title_full_unstemmed | Going Viral—RSV as the Neglected Adult Respiratory Virus |
title_short | Going Viral—RSV as the Neglected Adult Respiratory Virus |
title_sort | going viral—rsv as the neglected adult respiratory virus |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692430/ https://www.ncbi.nlm.nih.gov/pubmed/36422576 http://dx.doi.org/10.3390/pathogens11111324 |
work_keys_str_mv | AT busackbethany goingviralrsvastheneglectedadultrespiratoryvirus AT shorrandrewf goingviralrsvastheneglectedadultrespiratoryvirus |