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Do We Really Need Omicron Spike-Based Updated COVID-19 Vaccines? Evidence and Pipeline
The wild-type SARS-CoV-2 Spike-based vaccines authorized so far have reduced COVID-19 severity, but periodic boosts are required to counteract the decline in immunity. An accelerated rate of immune escape to vaccine-elicited immunity has been associated with Spike protein antigenic shifts, as seen i...
Autores principales: | Focosi, Daniele, Maggi, Fabrizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692555/ https://www.ncbi.nlm.nih.gov/pubmed/36366586 http://dx.doi.org/10.3390/v14112488 |
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