Structural Basis for the Immunogenicity of the C-Terminus of VP1 of Echovirus 3 Revealed by the Binding of a Neutralizing Antibody

Echovirus 3 (E3), a serotype of human enterovirus B (HEV-B), causes severe diseases in infants. Here, we determined the structures of E3 with a monoclonal antibody (MAb) 6D10 by cryo-EM to comprehensively understand the specificities and the immunological characteristic of this serotype. The solved...

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Detalles Bibliográficos
Autores principales: Qi, Shuai, Fu, Wangjun, Fan, Jinyan, Zhang, Li, Zheng, Binyang, Wang, Kang, Wang, Xiangxi, Zhu, Ling, Li, Xinjian, Zhang, Yuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692665/
https://www.ncbi.nlm.nih.gov/pubmed/36366420
http://dx.doi.org/10.3390/v14112322

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