Cargando…

The Reciprocal Relationship between Osteoporosis and Renal Stones

Previous studies have proposed an association between osteoporosis and renal stones. The current analyses intended to investigate the bidirectional relationship between osteoporosis and renal stones. The ≥40-year-old population in the National Health Insurance Service-Health Screening cohort (2002–2...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, So Young, Chung, Juyong, Park, Doo Sik, Yoo, Dae Myoung, Bang, Woo Jin, Choi, Hyo Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692876/
https://www.ncbi.nlm.nih.gov/pubmed/36431089
http://dx.doi.org/10.3390/jcm11226614
_version_ 1784837379641573376
author Kim, So Young
Chung, Juyong
Park, Doo Sik
Yoo, Dae Myoung
Bang, Woo Jin
Choi, Hyo Geun
author_facet Kim, So Young
Chung, Juyong
Park, Doo Sik
Yoo, Dae Myoung
Bang, Woo Jin
Choi, Hyo Geun
author_sort Kim, So Young
collection PubMed
description Previous studies have proposed an association between osteoporosis and renal stones. The current analyses intended to investigate the bidirectional relationship between osteoporosis and renal stones. The ≥40-year-old population in the National Health Insurance Service-Health Screening cohort (2002–2015) was analyzed. In study I, 67,811 patients with osteoporosis and 67,811 control I participants were matched. The hazard ratio (HR) of osteoporosis for renal stones was calculated using stratified Cox proportional hazard models. In study II, 25,261 patients with renal stones and 101,044 control II participants were matched. The HR of renal stones for osteoporosis was estimated using stratified Cox proportional hazard models. In study I, 3.4% (2276/67,811) of osteoporosis patients and 2.5% (1696/67,811) of control I participants had renal stones. Osteoporosis patients had a 1.36 times higher HR for renal stones than control I participants (95% confidence intervals [CI] = 1.28–1.45). In study II, 9.2% (2319/25,261) of renal stone patients and 7.6% (7658/101,044) of control II participants had osteoporosis. Renal stone patients had a 1.26 times higher HR for osteoporosis than control II participants (95% CI = 1.21–1.32). Adults with osteoporosis had a higher risk of renal stones. Moreover, adults with renal stones had a higher risk of osteoporosis.
format Online
Article
Text
id pubmed-9692876
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96928762022-11-26 The Reciprocal Relationship between Osteoporosis and Renal Stones Kim, So Young Chung, Juyong Park, Doo Sik Yoo, Dae Myoung Bang, Woo Jin Choi, Hyo Geun J Clin Med Article Previous studies have proposed an association between osteoporosis and renal stones. The current analyses intended to investigate the bidirectional relationship between osteoporosis and renal stones. The ≥40-year-old population in the National Health Insurance Service-Health Screening cohort (2002–2015) was analyzed. In study I, 67,811 patients with osteoporosis and 67,811 control I participants were matched. The hazard ratio (HR) of osteoporosis for renal stones was calculated using stratified Cox proportional hazard models. In study II, 25,261 patients with renal stones and 101,044 control II participants were matched. The HR of renal stones for osteoporosis was estimated using stratified Cox proportional hazard models. In study I, 3.4% (2276/67,811) of osteoporosis patients and 2.5% (1696/67,811) of control I participants had renal stones. Osteoporosis patients had a 1.36 times higher HR for renal stones than control I participants (95% confidence intervals [CI] = 1.28–1.45). In study II, 9.2% (2319/25,261) of renal stone patients and 7.6% (7658/101,044) of control II participants had osteoporosis. Renal stone patients had a 1.26 times higher HR for osteoporosis than control II participants (95% CI = 1.21–1.32). Adults with osteoporosis had a higher risk of renal stones. Moreover, adults with renal stones had a higher risk of osteoporosis. MDPI 2022-11-08 /pmc/articles/PMC9692876/ /pubmed/36431089 http://dx.doi.org/10.3390/jcm11226614 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kim, So Young
Chung, Juyong
Park, Doo Sik
Yoo, Dae Myoung
Bang, Woo Jin
Choi, Hyo Geun
The Reciprocal Relationship between Osteoporosis and Renal Stones
title The Reciprocal Relationship between Osteoporosis and Renal Stones
title_full The Reciprocal Relationship between Osteoporosis and Renal Stones
title_fullStr The Reciprocal Relationship between Osteoporosis and Renal Stones
title_full_unstemmed The Reciprocal Relationship between Osteoporosis and Renal Stones
title_short The Reciprocal Relationship between Osteoporosis and Renal Stones
title_sort reciprocal relationship between osteoporosis and renal stones
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692876/
https://www.ncbi.nlm.nih.gov/pubmed/36431089
http://dx.doi.org/10.3390/jcm11226614
work_keys_str_mv AT kimsoyoung thereciprocalrelationshipbetweenosteoporosisandrenalstones
AT chungjuyong thereciprocalrelationshipbetweenosteoporosisandrenalstones
AT parkdoosik thereciprocalrelationshipbetweenosteoporosisandrenalstones
AT yoodaemyoung thereciprocalrelationshipbetweenosteoporosisandrenalstones
AT bangwoojin thereciprocalrelationshipbetweenosteoporosisandrenalstones
AT choihyogeun thereciprocalrelationshipbetweenosteoporosisandrenalstones
AT kimsoyoung reciprocalrelationshipbetweenosteoporosisandrenalstones
AT chungjuyong reciprocalrelationshipbetweenosteoporosisandrenalstones
AT parkdoosik reciprocalrelationshipbetweenosteoporosisandrenalstones
AT yoodaemyoung reciprocalrelationshipbetweenosteoporosisandrenalstones
AT bangwoojin reciprocalrelationshipbetweenosteoporosisandrenalstones
AT choihyogeun reciprocalrelationshipbetweenosteoporosisandrenalstones