The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands

Since the discovery of vitamin D a century ago, a great number of metabolites, analogs, hybrids and nonsteroidal VDR ligands have been developed. An enormous effort has been made to synthesize compounds which present beneficial properties while attaining lower calcium serum levels than calcitriol. T...

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Detalles Bibliográficos
Autores principales: Maestro, Miguel A., Seoane, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692999/
https://www.ncbi.nlm.nih.gov/pubmed/36432615
http://dx.doi.org/10.3390/nu14224927
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author Maestro, Miguel A.
Seoane, Samuel
author_facet Maestro, Miguel A.
Seoane, Samuel
author_sort Maestro, Miguel A.
collection PubMed
description Since the discovery of vitamin D a century ago, a great number of metabolites, analogs, hybrids and nonsteroidal VDR ligands have been developed. An enormous effort has been made to synthesize compounds which present beneficial properties while attaining lower calcium serum levels than calcitriol. This structural review covers VDR ligands published to date.
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spelling pubmed-96929992022-11-26 The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands Maestro, Miguel A. Seoane, Samuel Nutrients Review Since the discovery of vitamin D a century ago, a great number of metabolites, analogs, hybrids and nonsteroidal VDR ligands have been developed. An enormous effort has been made to synthesize compounds which present beneficial properties while attaining lower calcium serum levels than calcitriol. This structural review covers VDR ligands published to date. MDPI 2022-11-21 /pmc/articles/PMC9692999/ /pubmed/36432615 http://dx.doi.org/10.3390/nu14224927 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Maestro, Miguel A.
Seoane, Samuel
The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands
title The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands
title_full The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands
title_fullStr The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands
title_full_unstemmed The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands
title_short The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands
title_sort centennial collection of vdr ligands: metabolites, analogs, hybrids and non-secosteroidal ligands
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692999/
https://www.ncbi.nlm.nih.gov/pubmed/36432615
http://dx.doi.org/10.3390/nu14224927
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