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Optimization of In Vivo Electroporation Conditions and Delivery of DNA Vaccine Encoding SARS-CoV-2 RBD Using the Determined Protocol

Vaccination against SARS-CoV-2 and other viral infections requires safe, effective, and inexpensive vaccines that can be rapidly developed. DNA vaccines are candidates that meet these criteria, but one of their drawbacks is their relatively weak immunogenicity. Electroporation (EP) is an effective w...

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Detalles Bibliográficos
Autores principales: Kisakov, Denis Nikolaevich, Kisakova, Lyubov Alexandrovna, Borgoyakova, Maria Borisovna, Starostina, Ekaterina Vladimirovna, Taranov, Oleg Svyatoslavovich, Ivleva, Elena Konstantinovna, Pyankov, Oleg Viktorovich, Zaykovskaya, Anna Vladimirovna, Shcherbakov, Dmitry Nikolaevich, Rudometov, Andrey Pavlovich, Rudometova, Nadezda Borisovna, Volkova, Natalia Vyacheslavovna, Gureev, Vadim Nikolaevich, Ilyichev, Alexander Alexeyevich, Karpenko, Larisa Ivanovna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693113/
https://www.ncbi.nlm.nih.gov/pubmed/36365078
http://dx.doi.org/10.3390/pharmaceutics14112259