A Modified Vancomycin Molecule Confers Potent Inhibitory Efficacy against Resistant Bacteria Mediated by Metallo-β-Lactamases

Multidrug-resistant bacterial infections mediated by metallo-β-lactamases (MβLs) have grown into an emergent health threat, and development of novel antimicrobials is an ideal strategy to combat the infections. Herein, a novel vancomycin derivative V(b) was constructed by conjugation of triazolylthi...

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Detalles Bibliográficos
Autores principales: Zhai, Le, Liu, Ya, Jiang, Yue, Kong, Ling-Yan, Xiao, Jian, Wang, Yi-Xue, Shi, Yang, Zhang, Yi-Lin, Yang, Ke-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693118/
https://www.ncbi.nlm.nih.gov/pubmed/36431786
http://dx.doi.org/10.3390/molecules27227685

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