Characterization of Three Variants of SARS-CoV-2 In Vivo Shows Host-Dependent Pathogenicity in Hamsters, While Not in K18-hACE2 Mice

Animal models are used in preclinical trials to test vaccines, antivirals, monoclonal antibodies, and immunomodulatory drug therapies against SARS-CoV-2. However, these drugs often do not produce equivalent results in human clinical trials. Here, we show how different animal models infected with som...

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Detalles Bibliográficos
Autores principales: Toomer, Gabriela, Burns, Whitney, Garcia, Liliana, Henry, Gerelyn, Biancofiori, Anthony, George, Albert, Duffy, Ciera, Chu, Justin, Sides, Morgan, Muñoz, Melissa, Garcia, Kelly, Nikolai-Yogerst, Anya, Peng, Xinjian, Westfall, Landon, Baker, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693146/
https://www.ncbi.nlm.nih.gov/pubmed/36423193
http://dx.doi.org/10.3390/v14112584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693146/
https://www.ncbi.nlm.nih.gov/pubmed/36423193
http://dx.doi.org/10.3390/v14112584

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