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Strategies for Solubility and Bioavailability Enhancement and Toxicity Reduction of Norcantharidin

Cantharidin (CTD) is the main active ingredient isolated from Mylabris, and norcantharidin (NCTD) is a demethylated derivative of CTD, which has similar antitumor activity to CTD and lower toxicity than CTD. However, the clinical use of NCTD is limited due to its poor solubility, low bioavailability...

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Detalles Bibliográficos
Autores principales: Liu, Qian, Sun, Henglai, Li, Xinyu, Sheng, Huagang, Zhu, Liqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693198/
https://www.ncbi.nlm.nih.gov/pubmed/36431851
http://dx.doi.org/10.3390/molecules27227740