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Structure- and Content-Dependent Efficiency of Cas9-Assisted DNA Cleavage in Genome-Editing Systems

Genome-editing systems, being some of the key tools of molecular biologists, represent a reasonable hope for progress in the field of personalized medicine. A major problem with such systems is their nonideal accuracy and insufficient selectivity. The selectivity of CRISPR-Cas9 systems can be improv...

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Detalles Bibliográficos
Autores principales:	Baranova, Svetlana V., Zhdanova, Polina V., Lomzov, Alexander A., Koval, Vladimir V., Chernonosov, Alexander A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693425/ https://www.ncbi.nlm.nih.gov/pubmed/36430368 http://dx.doi.org/10.3390/ijms232213889

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