Cytochromes P450 and P-Glycoprotein Phenotypic Assessment to Optimize Psychotropic Pharmacotherapy: A Retrospective Analysis of Four Years of Practice in Psychiatry

Altered cytochromes P450 enzymes (CYP) and P-glycoprotein transporter (P-gp) activity may explain variabilities in drug response. In this study, we analyzed four years of phenotypic assessments of CYP/P-gp activities to optimize pharmacotherapy in psychiatry. A low-dose probe cocktail was administer...

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Detalles Bibliográficos
Autores principales: Delage, Clément, Darnaud, Léa, Etain, Bruno, Vignes, Marina, Ly, Tu-Ky, Frapsauce, Alexia, Veyrier, Marc, Delavest, Marine, Marlinge, Emeline, Hennion, Vincent, Meyrel, Manon, Jacob, Aude, Chouchana, Margot, Smati, Julie, Pataud, Guillaume, Khoudour, Nihel, Fontan, Jean-Eudes, Labat, Laurence, Bellivier, Frank, Lloret-Linares, Célia, Declèves, Xavier, Bloch, Vanessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693601/
https://www.ncbi.nlm.nih.gov/pubmed/36579580
http://dx.doi.org/10.3390/jpm12111869

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