Mechanochemical Approach towards Multi-Functionalized 1,2,3-Triazoles and Anti-Seizure Drug Rufinamide Analogs Using Copper Beads

Highly regiospecific, copper-salt-free and neat conditions have been demonstrated for the 1,3-dipolar azide-alkyne cycloaddition (AAC) reactions under mechanochemical conditions. A group of structurally challenging alkynes and heterocyclic derivatives was efficiently implemented to achieve highly fu...

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Detalles Bibliográficos
Autores principales: Bhattacherjee, Dhananjay, Kovalev, Igor S., Kopchuk, Dmitry S., Rahman, Matiur, Santra, Sougata, Zyryanov, Grigory V., Das, Pralay, Purohit, Rituraj, Rusinov, Vladimir L., Chupakhin, Oleg N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693609/
https://www.ncbi.nlm.nih.gov/pubmed/36431885
http://dx.doi.org/10.3390/molecules27227784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693609/
https://www.ncbi.nlm.nih.gov/pubmed/36431885
http://dx.doi.org/10.3390/molecules27227784

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