Cargando…
Aminoquinolones and Their Benzoquinone Dimer Hybrids as Modulators of Prion Protein Conversion
Prion Diseases or Transmissible Spongiform Encephalopathies are neurodegenerative conditions associated with a long incubation period and progressive clinical evolution, leading to death. Their pathogenesis is characterized by conformational changes of the cellular prion protein—PrP(C)—in its infect...
Autores principales: | Costa, Amanda Rodrigues Pinto, Muxfeldt, Marcelly, Boechat, Fernanda da Costa Santos, de Souza, Maria Cecília Bastos Vieira, Silva, Jerson Lima, de Moraes, Marcela Cristina, Rangel, Luciana Pereira, Vieira, Tuane Cristine Ramos Gonçalves, Batalha, Pedro Netto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693643/ https://www.ncbi.nlm.nih.gov/pubmed/36432036 http://dx.doi.org/10.3390/molecules27227935 |
Ejemplares similares
-
The aggregation of mutant p53 produces prion-like properties in cancer
por: Rangel, Luciana P, et al.
Publicado: (2014) -
What is the role of lipids in prion conversion and disease?
por: Alves Conceição, Cyntia, et al.
Publicado: (2023) -
Discovery of 2-aminoquinolone acid derivatives as potent inhibitors of SARS-CoV-2
por: Shin, Young Sup, et al.
Publicado: (2023) -
Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressor
por: Silva, Jerson L., et al.
Publicado: (2013) -
Ligand Binding and Hydration in Protein Misfolding: Insights from Studies of Prion and p53 Tumor Suppressor Proteins
por: Silva, Jerson L., et al.
Publicado: (2009)