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How to Improve Solubility and Dissolution of Irbesartan by Fabricating Ternary Solid Dispersions: Optimization and In-Vitro Characterization

The purpose of this study is to improve the solubility and dissolution of a poorly soluble drug, Irbesartan, using solid dispersion techniques. For that purpose, different polymers such as Soluplus(®), Kollidon(®) VA 64, Kolliphor(®) P 407, and Polyinylpyrrolidone (PVP-K30) were used as carriers at...

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Detalles Bibliográficos
Autores principales: Akram, Aasma, Irfan, Muhammad, Abualsunun, Walaa A., Bukhary, Deena M., Alissa, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693646/
https://www.ncbi.nlm.nih.gov/pubmed/36365083
http://dx.doi.org/10.3390/pharmaceutics14112264