Cargando…

The influence of comorbid depression and overweight status on peripheral inflammation and cortisol levels

BACKGROUND: Depression and overweight are each associated with abnormal immune system activation. We sought to disentangle the extent to which depressive symptoms and overweight status contributed to increased inflammation and abnormal cortisol levels. METHODS: Participants were recruited through th...

Descripción completa

Detalles Bibliográficos
Autores principales:	McLaughlin, Anna P., Nikkheslat, Naghmeh, Hastings, Caitlin, Nettis, Maria A., Kose, Melisa, Worrell, Courtney, Zajkowska, Zuzanna, Mariani, Nicole, Enache, Daniela, Lombardo, Giulia, Pointon, Linda, Cowen, Philip, Cavanagh, Jonathan, Harrison, Neil, Bullmore, Edward, Pariante, Carmine M., Mondelli, Valeria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693673/ https://www.ncbi.nlm.nih.gov/pubmed/33731235 http://dx.doi.org/10.1017/S0033291721000088

Ejemplares similares

Childhood trauma, HPA axis activity and antidepressant response in patients with depression
por: Nikkheslat, Naghmeh, et al.
Publicado: (2020)

Augmentation therapy with minocycline in treatment-resistant depression patients with low-grade peripheral inflammation: results from a double-blind randomised clinical trial
por: Nettis, Maria Antonietta, et al.
Publicado: (2021)

Sex differences in a double-blind randomized clinical trial with minocycline in treatment-resistant depressed patients: CRP and IL-6 as sex-specific predictors of treatment response
por: Lombardo, Giulia, et al.
Publicado: (2022)

Higher immune-related gene expression in major depression is independent of CRP levels: results from the BIODEP study
por: Sforzini, Luca, et al.
Publicado: (2023)

Correction: Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study
por: Cattaneo, Annamaria, et al.
Publicado: (2020)

Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study
por: Cattaneo, Annamaria, et al.
Publicado: (2020)

The interaction between kynurenine pathway, suicidal ideation and augmentation therapy with minocycline in patients with treatment-resistant depression
por: Nettis, Maria Antonietta, et al.
Publicado: (2023)

Using quantitative MRI to study brain responses to immune challenge with interferon-α
por: Nettis, Maria Antonietta, et al.
Publicado: (2021)

Ketamine’s effect on inflammation and kynurenine pathway in depression: A systematic review
por: Kopra, Emma, et al.
Publicado: (2021)

PET imaging shows no changes in TSPO brain density after IFN-α immune challenge in healthy human volunteers
por: Nettis, M. A., et al.
Publicado: (2020)

Differential effect of interferon-alpha treatment on AEA and 2-AG levels
por: Zajkowska, Zuzanna, et al.
Publicado: (2020)

The Role of Peripheral Inflammation in Clinical Outcome and Brain Imaging Abnormalities in Psychosis: A Systematic Review
por: Kose, Melisa, et al.
Publicado: (2021)

Treatment-resistant depression and peripheral C-reactive protein
por: Chamberlain, Samuel R., et al.
Publicado: (2019)

Inflammation in cancer and depression: a starring role for the kynurenine pathway
por: Sforzini, Luca, et al.
Publicado: (2019)

The role of circulatory systemic environment in predicting interferon-alpha–induced depression: The neurogenic process as a potential mechanism
por: Borsini, Alessandra, et al.
Publicado: (2019)

Cortisol and inflammatory biomarker levels in youths with attention deficit hyperactivity disorder (ADHD): evidence from a systematic review with meta-analysis
por: Chang, Jane Pei-Chen, et al.
Publicado: (2021)

Exploring the role of immune pathways in the risk and development of depression in adolescence: Research protocol of the IDEA-FLAME study
por: Mondelli, Valeria, et al.
Publicado: (2021)

Persistent fatigue induced by interferon-alpha: a novel, inflammation-based, proxy model of chronic fatigue syndrome
por: Russell, Alice, et al.
Publicado: (2019)

No evidence for differential gene expression in major depressive disorder PBMCs, but robust evidence of elevated biological ageing
por: Cole, John J., et al.
Publicado: (2021)

A Modest Increase in (11)C-PK11195-Positron Emission Tomography TSPO Binding in Depression Is Not Associated With Serum C-Reactive Protein or Body Mass Index
por: Schubert, Julia J., et al.
Publicado: (2021)

Crosstalk between endocannabinoid and immune systems: a potential dysregulation in depression?
por: Boorman, Emily, et al.
Publicado: (2015)

Choroid plexus enlargement is associated with neuroinflammation and reduction of blood brain barrier permeability in depression
por: Althubaity, Noha, et al.
Publicado: (2021)

Cortisol and development of depression in adolescence and young adulthood – a systematic review and meta-analysis
por: Zajkowska, Zuzanna, et al.
Publicado: (2022)

Antenatal depression programs cortisol stress reactivity in offspring through increased maternal inflammation and cortisol in pregnancy: The Psychiatry Research and Motherhood – Depression (PRAM-D) Study
por: Osborne, S., et al.
Publicado: (2018)

What can neuroimmunology teach us about the symptoms of long-COVID?
por: Mondelli, Valeria, et al.
Publicado: (2021)

Transcriptomics in Interferon-α-Treated Patients Identifies Inflammation-, Neuroplasticity- and Oxidative Stress-Related Signatures as Predictors and Correlates of Depression
por: Hepgul, Nilay, et al.
Publicado: (2016)

Corrigendum to “Antenatal depression programs cortisol stress reactivity in offspring through increased maternal inflammation and cortisol in pregnancy: The Psychiatry Research and Motherhood – Depression (PRAM-D) study” [Psychoneuroendocrinology 98 (2018) 211–221]
por: Osborne, S., et al.
Publicado: (2020)

Peripheral inflammation is associated with micro-structural and functional connectivity changes in depression-related brain networks
por: Kitzbichler, Manfred G., et al.
Publicado: (2021)

Antidepressant Compounds Can Be Both Pro- and Anti-Inflammatory in Human Hippocampal Cells
por: Horowitz, Mark Abie, et al.
Publicado: (2015)

Cause or consequence? Understanding the role of cortisol in the increased inflammation observed in depression
por: Amasi-Hartoonian, Nare, et al.
Publicado: (2022)

Targeting inflammation in depression: Ketamine as an anti-inflammatory antidepressant in psychiatric emergency
por: Nikkheslat, Naghmeh
Publicado: (2021)

Cortisol and Inflammatory Biomarkers Predict Poor Treatment Response in First Episode Psychosis
por: Mondelli, Valeria, et al.
Publicado: (2015)

Genetic Contributions of Inflammation to Depression
por: Barnes, Jacob, et al.
Publicado: (2017)

T15. LONGITUDINAL ASSOCIATIONS BETWEEN CHILDHOOD SALIVARY CORTISOL LEVELS AND PRODROMAL SYMPTOMS IN LATE ADOLESCENCE: FINDINGS FROM A HIGH-RISK COHORT
por: Cullen, Alexis, et al.
Publicado: (2018)

Peripheral immune markers and antipsychotic non-response in psychosis
por: Enache, Daniela, et al.
Publicado: (2021)

Cortisol awakening response and diurnal cortisol among children at elevated risk for schizophrenia: Relationship to psychosocial stress and cognition
por: Cullen, Alexis E., et al.
Publicado: (2014)

S186. THE EFFECTS OF CHILDHOOD TRAUMA ON HIPPOCAMPAL VOLUME IN FIRST EPISODE PSYCHOSIS: DOES CORTISOL PLAY A ROLE?
por: Ciufolini, Simone, et al.
Publicado: (2020)

Cortisol Levels in Childhood Associated With Emergence of Attenuated Psychotic Symptoms in Early Adulthood
por: Cullen, Alexis E., et al.
Publicado: (2022)

The relationship between salivary C-reactive protein and cognitive function in children aged 11–14 years: Does psychopathology have a moderating effect?
por: Cullen, Alexis E., et al.
Publicado: (2017)

Increased Cortisol and Cortisone Levels in Overweight Children
por: Chu, Lanling, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_hinrccgh8soe3mihcbarmij8lv