Formulation of SARS-CoV-2 Spike Protein with CpG Oligodeoxynucleotides and Squalene Nanoparticles Modulates Immunological Aspects Following Intranasal Delivery

Nasal spray vaccination is viewed as a promising strategy for inducing both mucosal and systemic protection against respiratory SARS-CoV-2 coronavirus. Toward this goal, a safe and efficacious mucosal adjuvant is necessary for the transportation of the antigen across the mucosal membrane and antigen...

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Detalles Bibliográficos
Autores principales: Ho, Hui-Min, Huang, Chiung-Yi, Yang, Chung-Hsiang, Liu, Shih-Jen, Chen, Hsin-Wei, Yu, Guann-Yi, Chen, Jen-Kun, Chuang, Tsung-Hsien, Huang, Ming-Hsi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693849/
https://www.ncbi.nlm.nih.gov/pubmed/36432730
http://dx.doi.org/10.3390/pharmaceutics14112539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693849/
https://www.ncbi.nlm.nih.gov/pubmed/36432730
http://dx.doi.org/10.3390/pharmaceutics14112539

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